Comparison of Endometrial Protein Profile in Spontaneous Versus Stimulated Menstrual Cycles in Poor Responders

Distinct Endometrial Protein Profiles in Spontaneous and Stimulated Cycles in Women With Poor Ovarian Respons

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06804174

Enrollment

Registered

2025-02-03

Start date

2023-09-01

Completion date

2024-09-01

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Proteome

Keywords

endometrium, proteome, poor ovarian response, spontaneous cycle, stimulated cycle

Brief summary

Evaluation of endometrial protein profile in spontaneous and stimulated menstrual cycles

Interventions

OTHERuse of gonadotropins

Comparison of endometrial proteome during the window of implantation between stimulated and spontaneous cycles.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 43 Years

Healthy volunteers

Inclusion criteria

1. Primary infertility 2. Poor ovarian response

Exclusion criteria

1. Normal or high ovarian response to gonadotropin stimulation 2. Menstrual cycle disorders 3. Severe male cause of infertility 4. Preimplantation genetic testing 5. Pathological findings of the uterus (fibroids, endometrial polyps, adenomyosis) and fallopian tubes (distal occlusion of one or both fallopian tubes with hydrosalpinx).

Design outcomes

Primary

Measure	Time frame	Description
Analysis of endometrial proteome after the use of gonadotropins	From enrollment to the end of treatment (approximately 2 months).	Comparison of endometrial proteome during the window of implantation between spontaneous and stimulated cycles.

Countries

Slovenia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 20, 2026