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Dietary Acid Load and Oral Health Quality in Adolescents

Investigating the Relationship Between Dietary Acid Load and Oral Health-Related Quality of Life in Adolescents

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06803511
Enrollment
374
Registered
2025-01-31
Start date
2023-01-01
Completion date
2024-06-15
Last updated
2025-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adolescent

Keywords

Dietary acid load, oral health, quality of life, adolescents

Brief summary

This study investigates the link between dietary acid load and oral health-related quality of life in 374 high school students (226 females, 148 males). Participants completed a demographic questionnaire, the OHIP-14 scale, and provided 24-hour dietary recalls. Dietary acid load was assessed using PRAL and NEAP calculations. Data analysis was performed with SPSS 24 to explore the impact of diet composition on adolescents' oral health.

Detailed description

Introduction: Oral health plays a crucial role in the psychological and physical development of children and adolescents. The composition of the diet consumed significantly affects oral health. Objective: This study aimed to examine the relationship between dietary acid load and oral health-related quality of life in adolescents. Method: A total of 374 high school students (226 females, 148 males) participated in the study. Adolescents completed a demographic questionnaire and the Oral Health Impact Profile-14 (OHIP-14) scale, and 24-hour retrospective food consumption records were collected. Dietary acid load was assessed by calculating potential renal acid load (PRAL) and net endogenous acid production (NEAP) based on macronutrient and micronutrient intake from food records. Data analysis was conducted using the SPSS 24 software package.

Interventions

None listed

Sponsors

Ankara Yildirim Beyazıt University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
14 Years to 18 Years
Healthy volunteers
Yes

Inclusion criteria

* 14-18 ages

Exclusion criteria

* those with diagnosed eating disorders * those with diagnosed psychiatric * those with diagnosed cancer

Design outcomes

Primary

MeasureTime frameDescription
Oral Health Impact Profile-14 ScoreBaselineThis scale was used to assess the quality of life related to oral health and how oral health affects overall quality of life and general health. The scale consists of 14 items with 5-point Likert-type questions (each option ranging from 0 to 4 points) and was designed using a five-choice scaling method. It was concluded that as the total score increased, the severity of the problem also increased, leading to a decrease in quality of life.
Calculation of Dietary Acid LoadBaselineDietary acid load (DAL), potential renal acid load (PRAL), and net endogenous acid production (NEAP) were calculated based on the 24 hours food consumption record The formula for PRAL is as follows: PRAL (mEq/day) = 0.4888 x protein (g/day) +0.0366 x phosphorus (mg/day)-0.0205 x potassium (mg/day) - 0.0125 x calcium (mg/day) - 0.0263 x magnesium (mg/day) NEAP (mEq/day) = \[54.5 x protein (g/day) / potassium (mEq/day)\] - 10.2 High and positive PRAL and NEAP values indicate a high dietary acid load.

Secondary

MeasureTime frameDescription
Sociodemographic characteristicsBaselineSociodemographic characteristics will be assessed using a structured questionnaire developed by the researchers. The questionnaire will include items measuring age, gender, education level, and income status. The results will be presented as numbers and percentages for each characteristic.
Body Mass Index (BMI)BaselineKilograms per square meter (kg/m2)
HeightBaselineHeight in cm
Body weightBaselineBody weight in kg

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026