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Delivery Room Intervention and Evaluation Network

Delivery Room Intervention and Evaluation (DRIVE) Network

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06803498
Acronym
DRIVE Network
Enrollment
3000000
Registered
2025-01-31
Start date
2022-01-01
Completion date
2042-01-01
Last updated
2025-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant, Newborn, Resuscitation

Keywords

Continuous Positive Airway Pressure, Intermittent Positive Pressure Ventilation, Intubation, Intratracheal, Cardiopulmonary Resuscitation

Brief summary

The American Academy of Pediatrics (AAP) convened the multi-center Delivery Room Intervention and Evaluation (DRIVE) Network to establish essential infrastructure to collect, coordinate, and analyze core demographic, resuscitative, and outcome data for an inclusive and diverse population of infants who receive delivery room resuscitation at participating centers. The DRIVE Network consists of delivery hospitals across the United States, covering a range of geographic, urban/rural, racial/ethnic diversity across the country. Together, DRIVE seeks to compare practice-level delivery system characteristics, identify best practices, evaluate outcomes from various interventions, and promote professional development through dissemination via the wide reach of the Neonatal Resuscitation Program.

Detailed description

Basic neonatal resuscitation, which includes drying, warmth, stimulation, suctioning of the baby's nose/mouth as needed, and PPV, comprise the essential skills to which 95% of babies will respond and breathe, yet more data are collected about advanced resuscitative measures that occur in only 3-5% of deliveries. Existing neonatal networks and registries focus on high-risk and premature infants and are not all-inclusive of newborn babies and the basic neonatal resuscitation interventions which save the most lives, but about which little data have been collected in a standardized way. Studying quality of care at birth is also important as it is well known that there is variation between centers, as well as long-standing disparities in infant mortality in the United States. The objective of this project is to establish essential infrastructure to collect and coordinate core demographic, resuscitative, and outcome variables in an inclusive and diverse population of infants at participating centers. The overarching goal is to relay data back to individual centers, benchmarking their own results against the entire network. Individual centers can employ quality improvement techniques to target professional development activities and improve resuscitation practices. AAP would also use these data to continually improve the educational framework around NRP. Additionally, external investigators could also submit proposals to query the network database on important research questions involving neonatal resuscitation.

Interventions

PROCEDUREReceipt of significant resuscitation intervention at birth

Receipt of CPAP, PPV, intubation, or CPR at birth in a hospital delivery room

Sponsors

Children's Hospital of Philadelphia
CollaboratorOTHER
American Academy of Pediatrics
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
0 Days to 1 Days
Healthy volunteers
No

Inclusion criteria

Inborn infant in receipt of a significant resuscitation intervention (CPAP, PPV, intubation, or CPR) at birth

Exclusion criteria

Not live born

Design outcomes

Primary

MeasureTime frameDescription
Patient dispositionImmediately after the resuscitation interventionThe disposition of the patient after resuscitation including newborn nursery, neonatal ICU including a special care nursery or transitional nursery, palliative care, or transfer to other hospital

Secondary

MeasureTime frameDescription
In-hospital mortalityWithin 30 days after birthWhether the patient died following resuscitation

Countries

United States

Contacts

Primary ContactBeth Goins
bgoins@aap.org630-626-6289
Backup ContactJessica Weglarz, MBA
jweglarz@aap.org630-626-6037

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026