Blood Loss
Conditions
Keywords
Pregnancy blood loss
Brief summary
The primary objective is to assess in terms of frequency the adverse outcomes (premature birth, maternal-fetal haemorrhage, maternal fetal-neonatal death) of pregnancies of women attending the obstetric-gynaecological emergency department for genital bleeding beyond the 18th week of pregnancy.
Detailed description
The investigators decided to conduct this study because it is important on the one hand to carefully evaluate maternal-fetal outcomes in pregnancies characterised by genital bleeding in the second and third trimesters and on the other hand to evaluate the sonographic diagnostic capacity for identifying the aetiology of these genital bleedings, in order to understand whether the possibility of identifying a specific cause of the bleeding has also improved over time as sonographic techniques have improved. This could then allow management and subsequent obstetrical controls to be adapted in a more accurate and indivudualised manner. For the purpose of this study, no study-specific visits are planned. Data collected during pregnancy and delivery data for patients who gave birth at our centre will be analysed.
Interventions
None listed
Sponsors
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Pregnancy beyond 18 weeks gestational age complicated by genital bleeding; * Age of the patient ≥18 years; * Delivery at the O.U. of Obstetrics and Prenatal Age Medicine
Exclusion criteria
None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of preterm births | After delivery, up to 24 weeks |
| Frequency of antihemorrhagic therapy and maternal transfusions | Intra-partum and post-partum, up to 24 weeks |
| Rate of hospitalization for genital blood loss | After the 18th week of pregnancy |
| Average length of hospitalization in hours | During Hospitalization, up to 24 weeks |
| Percentage of spontaneous deliveries, operative vaginal, cesarean sections (elective, urgent, emergent) | After delivery, up to 24 weeks |
| Frequency of live births, average APGAR, average pH of umbilical artery or vein, average neonatal weight | After delivery, up to 24 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of finding abnormal ultrasound findings corresponding to the etiology of bleeding | During the obstetric ultrasound performed at the time of admission | To assess whether the ultrasound capability in detecting a specific etiology of bleeding has improved over time in conjunction with the evolution of technology and resolution of ultrasound equipment. |
Countries
Italy
Contacts
Primary ContactElisa Montaguti, MD
Outcome results
None listed