Skip to content

Changes in the Carbon Dioxide Content in the Body During a Simulated Avalanche Burial With and Without the Use of a Breathing Tube System.

Changes in Systemic Carbon Dioxide Levels During Simulated Avalanche Burial Using a One-way Valve Device: a Double Blinded, Randomized Cross-over Trial

Status
Enrolling by invitation
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06802744
Acronym
Avalanox
Enrollment
10
Registered
2025-01-31
Start date
2025-02-07
Completion date
2025-03-31
Last updated
2025-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Avalanche Burial

Keywords

AAPD, Artificial air-pocket device

Brief summary

Every year, around 100 people die in avalanches in the Alps. Many of these accidents occur during winter sports. In most cases, the victims suffocate under the snow after the avalanche has come to a standstill. A key survival factor here is the time it takes to be rescued. If a buried victim is rescued within 15 minutes, the probability of survival is over 90%. After 35 minutes, however, this drops drastically to just 30%. A modern avalanche rescue system, such as the AvaLung-device, could extend the survival time. The system directs the exhaled air via a tube to the back of the buried person so that no toxic CO2 concentrations build up in the available breathing cavity. It is also intended to prevent the formation of an ice mask, which can impair the release of oxygen from the snow. This study investigates whether the AvaLung system can extend the survival time in the event of burial. The aim is to test the effects of such a breathing tube system. The oxygen and carbon dioxide levels of the test subjects are measured while they are buried in a simulated avalanche - once with and once without the AvaLung system. In addition, it is investigated how long it takes before the buried subjects have to stop the examination, for example due to shortness of breath or deteriorating respiratory gases in the blood. Test setup: The test subjects lie on their backs with their heads and chests buried under snow. During the test phase, various parameters are continuously monitored, such as the breathing rate and the CO2 concentration in the blood. A comparative study is carried out: once with a functioning rescue system, and once with a manipulated (non-functioning) system. Expected benefit: The results of this study should contribute to a better understanding of the effectiveness of avalanche rescue systems and thus increase the chances of survival of avalanche victims in the future. This is particularly important today, as the number of winter sports enthusiasts and the number of avalanches triggered by them is constantly increasing.

Interventions

DEVICEAddition of an artificial air-pocket device during simulated avalanche burial

In contrast to the control group, the subjects in this arm are provided with a functioning device that directs the exhaled air away from the area of the respiratory cavity.

DEVICEAddition of a non-functioning artificial air-pocket device during simulated avalanche burial

In contrast to the intervention arm, the subjects in this arm are provided with a non-functioning artificial air-pocket device which does not redirect the exhaled air away from the breathing-cavity.

Sponsors

Klinik fur Pneumologie und Schlafmedizin Kantonsspital Aarau
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Adults over 18 * Able to consent

Exclusion criteria

* Anamnestic evidence of previous pulmonary or cardiac disease * Known neuromuscular diseases * Thoracic deformities * Acute respiratory infections * In women: Pregnancy (excluded by history and urine test) * Age over 60 Years * Presence of claustrophobia

Design outcomes

Primary

MeasureTime frame
Course of PtCO2 measured transcutaneously45 minutes

Secondary

MeasureTime frame
Course of PetCO245 minutes
Progression of respiratory minute volume45 minutes
Course of the body temperature45 minutes
Heart rate progression and variability45 minutes
Burial time until the test is terminated45 minutes
Course of PetO245 minutes
Course of SpO245 minutes
Progression of Respiratory rate45 minutes
Course of PtO245 minutes

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026