Fatty Liver Disease, Liver Inflammation
Conditions
Brief summary
To evaluate the correlation between LivQ-box® parameters carried by iLivTouch and liver inflammation in patients with NAFLD, as well as the diagnostic value of liver inflammation of different severity levels.
Detailed description
This study is a multi-center study that retrospectively analyzed and prospectively included 240 NAFLD patients in total who met the inclusion criteria. The laboratory, iLivTouch, and liver biopsy results were collected to evaluate the correlation between LivQ-box® parameters carried by iLivTouch and liver inflammation in patients with NAFLD, as well as the diagnostic value of liver inflammation of different severity levels. In the end, cut-off values for different stages of inflammation were obtained.
Interventions
None listed
Sponsors
Beijing Tsinghua Changgeng Hospital
Wuxi Hisky Medical Technology Co Ltd
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients diagnosed with NAFLD according to The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases; * Age over 18 years old, gender not limited; * Not combined with liver diseases (such as viral hepatitis, drug-induced liver injury, autoimmune liver disease); * Perform iLivTouch examination within ± 14 days of liver pathology examination; * No history of excessive alcohol consumption (converted to ethanol:\<140g/week for males,\<70g/week for females);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the correlation and diagnostic performance of LivQ-box and cut-off values for different inflammation stages in NAFLD patients based on iLivTouch. | 12 months |
Countries
China
Contacts
Primary ContactLai Wei
Outcome results
None listed