Cardiovascular, Menopause
Conditions
Brief summary
Background: The present study aimed to examine the effects of a 26-week multicomponent exercise program on lipid and lipoprotein profiles, blood pressure, and anthropometric parameters in healthy but sedentary premenopausal and postmenopausal women aged 40-60. Method: The program, comprising resistance, balance, flexibility, and aerobic exercises, aimed to identify group-specific responses and establish the program's efficacy in mitigating cardiovascular risks. Seventy-five women were recruited, and 38 completed the intervention. Participants were categorized into premenopausal (n=18), postmenopausal (n=10), and control groups (n=10). Key measures included total cholesterol, low- and high-density lipoprotein cholesterol, triglycerides, glucose, systolic and diastolic blood pressure, and anthropometric variables. Statistical analyses employed the Shapiro-Wilk test, paired t-tests, Wilcoxon tests, and Kruskal-Wallis tests, with α=0.05.
Interventions
OTHERExperimental: Pre-Menopausic
The physical exercise program, lasting for 26 weeks, was conducted with an uninterrupted weekly frequency of 3 sessions, on non-consecutive days, in the late afternoon (at 7:30 PM), each lasting 60 minutes.
OTHERExperimental: Post- Menopausic
The physical exercise program, lasting for 26 weeks, was conducted with an uninterrupted weekly frequency of 3 sessions, on non-consecutive days, in the late afternoon (at 7:30 PM), each lasting 60 minutes.
Sponsors
University of Évora
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
FEMALE
Age
40 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* women aged between 40 and 60 years old; * healthy, asymptomatic, and non-smoking; * medical diagnosis favouring the engagement in physical-sporting activities; * absence of clinical history related to alcoholism or uncontrolled metabolic disease; * no clinical prescription for hypotensive pharmacological intake, cholesterol reduction, hormonal replacement therapy, or any other intervention capable of inducing alterations in lipid and lipoprotein metabolism; or * abnormal blood sample results.
Exclusion criteria
* non-fulfilment of inclusion criteria; * clinical history characterized by symptoms related to cardiovascular disease (CVD), including stroke (CVA) and coronary vascular disease (CVD), renal or hepatic disease, musculoskeletal disorders, or rheumatoid conditions that may impede full participation in the exercise program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Cholesterol | 26-week |
| Low-density lipoprotein Cholesterol | 26-week |
| High-density lipoprotein Cholesterol | 26-week |
| Triglycerides | 26-week |
| Castelli Risk Index I | 26-week |
| Castelli Risk Index II | 26-week |
| Very Low-Density Lipoprotein Cholesterol | 26-week |
| Glucose | 26-week |
| Systolic Blood Pressure | 26-week |
| Diastolic Blood Pressure | 26-week |
| Heart Rate | 26-week |
| Body Mass Index | 26-week |
| Waist Circumference | 26-week |
| Hip Circumference | 26-week |
| Waist Circumference/ Hip Circumference | 26-week |
Countries
Portugal
Outcome results
None listed