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Effect of Continuous Adductor Canal Block Versus Continuous Adductor Canal Block With Additional Infiltration Between The Popliteal Artery and Capsule of The Knee (IPACK) After Arthroscopic Knee Surgeries

A Comparative Study Between the Effect of Continuous Adductor Canal Block Versus Continuous Adductor Canal Block With Additional Infiltration Between The Popliteal Artery and Capsule of The Knee (IPACK) After Arthroscopic Knee Surgeries

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06802419
Enrollment
70
Registered
2025-01-31
Start date
2025-01-30
Completion date
2025-10-01
Last updated
2025-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Continuous Adductor Canal Block, Infiltration Between The Popliteal Artery and Capsule of The Knee, Arthroscopic Knee Surgeries

Brief summary

This study aims to evaluate the effect of Continuous Adductor Canal Block only versus adding posterior knee block, known as the Infiltration between the Popliteal Artery and Capsule of the Knee (IPACK) block with Continuous Adductor Canal Block (CACB) after arthroscopic knee surgeries.

Detailed description

Enhanced recovery after arthroscopic knee surgery is gaining popularity in orthopedic surgeries. Motor preservation with adequate analgesia has become the optimal postoperative goal, enabling earlier physical therapy, faster recovery, and early hospital discharge. Spinal anesthesia for knee arthroscopy has favorable outcome effects compared with general anesthesia. The positive physiological effects of the provided sympathetic blockade with less blood loss, increased leg blood flow, and better initial pain relief explain this. An ideal nerve block that targets the sensory nerves and spares the motor function can facilitate early ambulation and rehabilitation, a major goal for patients undergoing arthroscopic knee surgery. A novel technique for posterior knee block, known as the infiltration between the popliteal artery and capsule of the knee (IPACK) block combined with continuous adductor canal block (CACB) would reduce opioid requirements.

Interventions

Patients will receive continuous adductor canal block.

OTHERContinuous Adductor Canal Block with additional Infiltration between The Popliteal Artery and Capsule

Patients will receive Continuous Adductor Canal Block with additional Infiltration between The Popliteal Artery and Capsule of The Knee

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
21 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Age from 21 to 65 years. * Both sexes. * American Society of Anesthesiologists (ASA) Physical Status Class I to II. * Patients with successful spinal anesthesia. * Patients scheduled for elective arthroscopic knee surgery for anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) repair.

Exclusion criteria

* Declining to give written informed consent. * History of allergy to the medications used in the study. * Contraindications to regional anesthesia (including coagulopathy and local infection). * Polytrauma patients having lower limb fractures. * Patients with pre-existing myopathy or neuropathy on the operating limb. * Patients with diabetes mellitus. * Psychiatric disorder. * Morbid obesity \[body mass index (BMI) \> 45kg/m2\]. * Complicated Surgery.

Design outcomes

Primary

MeasureTime frameDescription
Degree of pain24 hours postoperativelyThe degree of pain will be assessed using the Visual Analogue Scale (VAS). VAS score is determined by measuring the distance (mm) on the 10-cm line between the no pain anchor and the patient's mark, providing a range of scores from 0-100. No pain (0-4 mm), mild pain (5-44 mm), moderate pain (45-74 mm), and severe pain (75-100 mm).

Secondary

MeasureTime frameDescription
Total Nalbuphine consumption24 hours postoperativelyRescue analgesia will be given when VAS score ≥ 30 mm, in the form of IV injection of 10 mg Nalbuphine. Followed by reassessment of pain after 10 minutes, a second dose of Nalbuphine will be given if still VAS score ≥ 30 mm.
Straight leg rise24 hours postoperativelyStraight leg rise (SLR) will be recorded.
Range of motion24 hours postoperativelyRange of motion (ROM) will be recorded
Rate of complications24 hours postoperativelyRate of complications like falling will be recorded

Countries

Egypt

Contacts

Primary ContactNada E Hussein, Master
Nadahussein@med.asu.edu.eg00201112449418

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026