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Effects of Different Walking Exercises on Pain, Physical Performance and Balance in Knee Osteoarthritis

The Effects of Forward and Backward Treadmill Walking Exercises in Addition to Conventional Physiotherapy on Pain, Physical Performance and Balance in Knee Osteoarthritis

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06802107
Enrollment
90
Registered
2025-01-31
Start date
2025-01-15
Completion date
2025-12-30
Last updated
2025-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

knee osteoarthritis, Walking, Treadmill, Backward, Forward

Brief summary

The aim of this study is to investigate and compare the effects of forward and backward walking exercises on treadmill in addition to traditional physiotherapy interventions on pain, physical performance and balance in patients with knee osteoarthritis. Secondarily, it is aimed to investigate the effects of walking on spatio-temporal parameters, knee joint position sense, range of motion, quadriceps, hamstring and hip adductors muscle strength, Q angle, quality of life and kinesiophobia.

Detailed description

Knee osteoarthritis is a common degenerative joint disease in the world and causes varying degrees of loss of function in individuals in terms of pain, physical performance and balance ability due to the wear and tear in the joint cartilage. Exercise practices play a critical role in the management of knee osteoarthritis and various types of exercises are used to alleviate the symptoms of the disease. One of the exercises used in this context is walking. Today, various modified or designed walking training programs such as walking on land/water, weight-supported walking, positive pressure walking, walking on a treadmill, walking forward-backward, and walking uphill can be applied in the rehabilitation of individuals with osteoarthritis. Exercises done on a treadmill offer individuals the opportunity to exercise safely in a controlled environment. In addition, forward and backward walking exercises done on a treadmill have the potential to improve balance and coordination by activating different muscle groups. Such dynamic exercises can facilitate the daily activities of osteoarthritis patients and increase their physical activity levels. Some biomechanical research results on backward walking in recent years are quite interesting. It is stated that the quadriceps muscle works more concentrically and isometrically while the eccentric load decreases during backward walking and can be used to increase and strengthen the stability of the knee. In addition, according to studies conducted in recent years, walking backwards is a useful strategy to reduce knee load compared to forward walking. In light of these findings, it is a walking exercise type that is thought to be more effective for knee osteoarthritis rehabilitation. However, although there are many studies on the effects of walking exercise in knee osteoarthritis rehabilitation, there are very few studies on backward walking in knee osteoarthritis. At the same time, it is unclear whether walking backwards provides an additional clinical benefit compared to walking forward in patients with knee osteoarthritis. In addition, there is no study comparing the effects of walking backwards and walking forward on the treadmill on pain, physical performance and balance, and there is a serious gap in the literature on this subject. In light of this information in the literature, the primary purpose of this study is to investigate and compare the effects of walking forwards and backwards on the treadmill in patients with knee osteoarthritis on pain, physical performance and balance. Secondarily, the effects of gait on spatio-temporal parameters, knee joint position sense, range of motion, quadriceps, hamstring and hip adductors muscle strength, Q angle, quality of life and kinesiophobia will also be investigated.

Interventions

BEHAVIORALBackward-treadmill Walking

A backward walking program will be applied on the treadmill. To be done 3 times a week / 8 weeks. Before the walking exercises, 5 minutes of warm-up and 5 minutes of cool-down exercises will be performed. While walking on the treadmill, the participant can hold onto the railings. Each participant will start at the speed they choose and gradually increase their perceived exertion rate to 11-13 on the Borg scale, and it is planned to walk for 10 minutes in the first week and gradually for 20-30 minutes in the following weeks.

BEHAVIORALForward-treadmill Walking

A forward walking program will be applied on the treadmill. To be done 3 times a week / 8 weeks. Before the walking exercises, 5 minutes of warm-up and 5 minutes of cool-down exercises will be performed. While walking on the treadmill, the participant can hold onto the railings. Each participant will start at the speed they choose and gradually increase their perceived exertion rate to 11-13 on the Borg scale, and it is planned to walk for 10 minutes in the first week and gradually for 20-30 minutes in the following weeks.

OTHERTraditional physiotherapy

Traditional physiotherapy is a treatment method that includes exercise training, hotpack, ultrasound and TENS (electrotherapy) applications. To be done 3 times a week / 8 weeks. 20 min hotpack + 7 min ultrasound + 20 min TENS and knee osteoarthritis exercises (hip knee flexion extension, knee extension while sitting on a chair, quadriceps isometric exercise in the supine position, straight leg raise exercises) are planned to be applied in the clinic with the physiotherapist. The exercises are planned to be started with 5 repetitions in the first week and the intensity of the exercise is planned to be increased with 10 repetitions, 15 repetitions and 20 repetitions depending on the patient's tolerance.

Sponsors

Hasan Kalyoncu University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
40 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosed with knee OA * According to the Kellgren Lawrence scale, grade I-II-III knee OA * VAS score above 3

Exclusion criteria

* Knee pain caused by other diseases (rheumatoid arthritis, gouty arthritis, etc.) * History of lower extremity surgery * Receiving physical therapy within the last 6 months * A medical condition that prevents safe exercise * Intra-articular injection (hyaluronic acid/steroid) application within the last 6 months * Diabetic neuropathy * Active and regular exercise, * Not volunteering to participate in the study * Patients with osteoporosis

Design outcomes

Primary

MeasureTime frameDescription
Pain8 weeksIt will be evaluated with the visual analog scale (VAS). VAS consists of a horizontal 10 cm long line, where 0 (zero) indicates no pain and 10 indicates unbearable pain. The patient is asked to indicate where their condition fits on this line by drawing a line, putting a dot or pointing.
Physical Function and Performance Measures8 weeksWestern Ontario and McMaster Üniversiteleri Osteoartrit İndeksi (WOMAC) WOMAC is a self-reported health status measure developed to assess pain, joint stiffness, and function in patients with hip and knee osteoarthritis. It questions patients on three separate clinical dimensions: pain, joint stiffness, and function. It contains a total of 24 questions. The three subdimensions that make up the scale can be scored individually or as a total. Higher scores represent worse pain, physical function, and stiffness.
balance8 weeksTimed up and go test This test measures the dynamic balance and functional mobility. It is a test that measures the time in seconds for the individual to stand up from a standard chair (seat height of approximately 44 cm, arm height 65 cm), walk a distance of 3 meters, turn around and sit on the chair.

Secondary

MeasureTime frameDescription
Q açısı8 weeksIt is planned to be measured with a universal goniometer. The pivot point of the goniometer is placed at the center of the patella, the fixed arm pointing to the tibia tuberosity and the movable arm pointing to the SIAS, and the angle between the line drawn from the SIAS to the middle of the patella and the two lines drawn from the middle of the patella to the tibia tuberosity is recorded.
Kinesiophobia8 weeksTampa Kinesiophobia Scale It was developed to evaluate the kinesiophobia of individuals. The scale consists of 17 questions. When calculating the scale score, the scores of some questions are reversed and calculated. A high total score indicates that the individual has high kinesiophobia.
knee joint position sense8 weeksJoint position sense (JPS) is evaluated by the angular difference between a repeatedly determined target position and the predicted position, and this is called absolute angular error. This method is a reliable technique for the knee joint. JPS is tested by actively finding the joint position that was previously taught passively. In the study, 60° knee flexion were determined as target angles. It is planned to use a universal goniometer for the test.
Spatio-temporal variables of gait8 weeksGaı̇t Analyzer application A smartphone-based application called Gait Analyzer will be used. It collects kinematic data of gait using smartphone technology and phone sensors. With this application, kinematic data of walking such as walking speed, cadence, step duration, step length, step length symmetry and step duration symmetry can be obtained. The smartphone is fixed to the region corresponding to the L3 proccesus spinosus of the patient with a suitable waist belt with velcro bandage. The patients are then asked to walk a distance of 20 meters at their natural gait and speed without walking aids and measurements are performed.
Quality of life8 weeksEUROQL 5d 5l The scale consists of two parts: the EQ-5D descriptive system and the EQ-VAS (visual analog scale).
Knee Range of Motion Assessment8 weeksKnee flexion and extension will be measured with a universal goniometer.
Quadriceps, Hamstring and hip adduction strength8 weeksIsometric muscle strength will be assessed with a hand-held dynamometer.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026