The Value of 68Ga-FAPI PET/CT in Detecting Recurrent and Metastatic Lesions in Patients with Thyroid Cancer After Surgery

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06800768

Enrollment

Registered

2025-01-30

Start date

2025-02-01

Completion date

2030-01-31

Last updated

2025-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Cancer

Keywords

Thyroid Cancer, 68Ga-FAPI, PET/CT

Brief summary

This study aims to investigate the value of 68Ga-FAPI PET/CT in detecting recurrent and metastatic lesions in patients with thyroid cancer after surgery.

Detailed description

The investigators will number all participants, create a medical record file, and record their basic information (gender, age) as well as contact information and medical history information. All participants will undergo a 68Ga-FAPI PET/CT when recurrence or metastasis is suspected. The imaging response measurements will be compared with follow-up results or histopathological findings as the gold standard.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

1. Patients with thyroid cancer who have undergone surgery and are suspected of recurrence or metastasis during clinical evaluation. 2. Signed and dated informed consent form. 3. Commitment to comply with research procedures and co-operation in the implementation of the full research process. 4. Aged 18-80 years old.

Exclusion criteria

1. Patients with serious illnesses that researchers consider unsuitable for participation in this clinical study. Such as severe heart and lung failure, severe bone marrow suppression, severe liver and kidney dysfunction, etc. 2. Intestinal perforation, complete intestinal obstruction. 3. Pregnant women and women who may be pregnant, women who are breastfeeding. 4. Non-compliant person.

Design outcomes

Primary

Measure	Time frame	Description
Diagnosis of recurrent or metastatic thyroid cancer	Within 1 week after enrollment	The value of 68Ga-FAPI PET/CT in detecting recurrent and metastatic lesions in patients with thyroid cancer after surgery

Secondary

Measure	Time frame	Description
Standardized uptake value(SUV)	Within 1 week after enrollment	SUV of 68Ga-FAPI uptake on PET/CT images for tumor lesions
Disease free survival	3 years	Disease free survival

Countries

China

Contacts

Primary ContactJiajia Hu

jiajiahu@shsmu.edu.cn13524945287

Outcome results