Hemodialysis, Kidney Failure, Overhydration
Conditions
Keywords
hemodialysis, water-electrolyte balance, dry body mass, skinfold thickness
Brief summary
Background Maintaining fluid balance is one of major challenges of the dialysis therapy. It includes, in particular, the management of dry body mass. We postulated that simple measurement of subscapular skinfold thickness before and after hemodialysis could help monitor hydration status in chronic dialysis patients. Aim of the study The aim of the study was to compare the conventional methods of monitoring hydration status during hemodialysis with an assessment of skin fold thickness. Materials and Methods 50 participants (21 F, 29 M; age 60 ±15 years) were enrolled. Directly before the hemodialysis session the following parameters were measured: body composition with bioimpedance spectroscopy, skinfold thickness in subscapular area with standardized caliper and blood tests: blood count, urea, n-terminal pro B-type natriuretic peptide (nt-proBNP) and pro-adrenomedullin (pro-ADM). The procedures were repeated at the end of three consecutive hemodialysis sessions.
Interventions
there were assessed three consecutive hemodialysis sessions
Sponsors
Medical University of Lodz
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* chronic hemodialysis for at least 3 months
Exclusion criteria
* severe mental disabilities, poor compliance, any acute infection, instability of the cardiovascular hemodynamic condition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes in overhydration | From enrollment to one week |
Countries
Poland
Outcome results
None listed