Autonomic Dysfunction in Patients With Migraine: Cardiovascular and Neurophysiology Assessment

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06798259

Enrollment

116

Registered

2025-01-29

Start date

2025-01-07

Completion date

2025-09-30

Last updated

2025-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine Headache

Brief summary

Autonomic dysfunction in patients with migraine: cardiovascular and neurophysiology assessment.

Detailed description

assessment if Autonomic dysfunction in patients with migraine by using cardiovascular assessment by HOTLER MONITORING and table tilt test and neurophysiology assessment by sympathetic skin response

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* 1.fulfilling ICHD-3 criteria for migraine 2. migraine for at least 3 months.

Exclusion criteria

brain imaging showing structural brain lesions. .medications that could impact autonomic function such as tricyclic antidepressants, anticholinergics, or opioids. * Patients with concomitant medical illness causing autonomic dysfunction such as: diabetes, cardiovascular, demyelinating or degenerative neurological disorders. * Contraindications for performing the tilt test * Pregnant patients.

Design outcomes

Primary

Measure	Time frame	Description
Autonomic dysfunction in patients with migraine	baseline	assessment of autonomic dysfunction using Composite autonomic system Score 31

Secondary

Measure	Time frame	Description
Cardiovascular assessment	24 hours	Cardiovascular is done using Holter monitoring and table tilt est

Countries

Egypt

Outcome results