Diquat Poisoning, Toxic Encephalopathy
Conditions
Brief summary
This ambispective cohort study aims to characterize the relationship between plasma diquat concentrations and organ damage risk.
Interventions
PROCEDUREextracorporeal treatment
Extracorporeal treatments included hemoperfusion (HP) and continuous veno-venous hemodiafiltration (CVVHDF).
Sponsors
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. history of oral exposure to diquat solution reported by patient or proxy; 2. a specimen for the diquat plasma concentration collected immediately upon admission; 3. documentation that patients or, in case of unconsciousness of the patient, legal proxies were aware of and agreed to treatment plans.
Exclusion criteria
1. they had ingested other toxins in addition to diquat (qualitative toxicological screening tests); 2. diquat was not detected in specimens, or plasma concentration data were unavailable; 3. patients with an exposure time (time from exposure to emergency department presentation) longer than 48 hours; 4. data on organ damage were not unavailable; 5. combined with other central nervous system injuries other than toxic encephalopathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival outcome | 28 days within the index date of presentation at emergency department |
Countries
China
Outcome results
None listed