Risk Factors of Paraspinal Muscles in Degenerative Lumbar Spondylolisthesis

Prediction of Risk Factors of Paraspinal Muscles in Degenerative Lumbar Spondylolisthesis Based on Spine MRI

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06797700

Acronym

RFPMDLS

Enrollment

1000

Registered

2025-01-28

Start date

2025-03-06

Completion date

2025-08-31

Last updated

2025-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spine Degeneration

Keywords

degenerative lumbar spondylolisthesis, paraspinal muscles, MRI

Brief summary

This is a retrospectively observational study. The goal of this observational study is to analyze the risk factors of paraspinal muscles associated with the occurrence of spondylolisthesis in patients with degenerative lumbar spondylolisthesis(DLS) and to construct a predictive model. The main question it aims to answer is: Which paraspinal muscle changes are risk factors for DLS? We will collect the information of patients who have undergone lumbar MRI in our hospital and have been diagnosed with back pain ( including spondylolisthesis or no spondylolisthesis) during the period from 2022 to 2024.The collected data included gender, age, body mass index (BMI), diabetes, hypertension, occupation and imaging parameters. We will then retrospectively analyze the risk factors associated with lumbar spondylolisthesis.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patients who presented to our hospital with back pain(the diagnosis was spondylolisthesis or no spondylolisthesis); * Patients older than 50 years; * Patients with complete clinical data and magnetic resonance imaging (MRI) before surgery.

Exclusion criteria

* The patient has previous spinal surgery; * Patients with lumbar tumor,lumbar infection and lumbar tuberculosis; * Patients with incomplete MRI sequence.

Design outcomes

Primary

Measure	Time frame	Description
the MF CSA	Two weeks before treatment	the total cross-sectional areas of the multifidus muscl.Measurement it on axial T2-weighted magnetic resonance (MR) images from the L4 vertebral body levels
the ES CSA	Two weeks before treatment	the total cross-sectional areas of the erector spinae.Measurement it on axial T2-weighted magnetic resonance (MR) images from the L4 vertebral body levels
the MF FCSA	Two weeks before treatment	The functional cross-sectional areas of the multifidus muscl.Measurement it on axial T2-weighted magnetic resonance (MR) images from the L4 vertebral body levels
the ES FCSA	Two weeks before treatment	The functional cross-sectional areas of the erector spinae.Measurement it on axial T2-weighted magnetic resonance (MR) images from the L4 vertebral body levels

Secondary

Measure	Time frame	Description
SMI	Two weeks before treatment	The skeletal muscle index.SMI = l CSA of muscle on an axial scan (expressed as cm2) divided by the square of the patient's height (expressed as cm2).

Countries

China

Contacts

Primary ContactXinyun Li

15750359757@163.com86+15750359757

Outcome results