Fetal Ovarian Cyst
Conditions
Keywords
ultrasound
Brief summary
The goal of this observational study is to investigate whether there are any prenatal ultrasound features that may predict the need for postnatal surgery versus spontaneous regression of such formations, so that better counseling can be provided to parents even in the prenatal period.
Detailed description
The rationale of the study is to define the role of prenatal ultrasonography in diagnostic framing and prognostic guidance in cases of suspected fetal ovarian cyst detection. Prenatal ultrasonography in such cases detects the presence of a pelvic formation in female fetuses, although the differential diagnosis is not always straightforward and can only be placed with certainty in the postnatal period. The investigators will therefore retrospectively assess postnatal outcomes in newborns prenatally diagnosed with ovarian cysts and investigate the presence of any prenatal ultrasound findings most associated with an unfavorable postnatal prognosis in terms of need for surgery and fetal complications. This will allow the investigators to more precisely delineate the timing of serious prenatal ultrasound checks once the diagnosis of fetal ovarian cyst is established. Ultrasound follow-up has been performed in all infants with prenatal ultrasound suspicion of ovarian cyst and continues until the cyst disappears, which occurs on average within the first six to 12 months of life. Follow-up therefore is generally 12 months, but may be discontinued early in case of earlier resolution of the cyst.
Interventions
None listed
Sponsors
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 44 Years
Inclusion criteria
* Single pregnancy * Age greater than or equal to 18 years * Detection of suspected fetal ovarian cyst on ultrasonography * Performance of delivery at the division of Obstetrics and Prenatal Age Medicine
Exclusion criteria
None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Association between ovarian cyst characteristics and the performance of cyst excision surgery on the newborn. | Up to 100 weeks | The outcome of the primary aim will be the percentage of infants who underwent surgery vs those in whom the formation went into spontaneous regression |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postnatal Outcomes | Up to 100 weeks | Description of the cohort of fetuses prenatally diagnosed with suspected ovarian cyst |
| Changes in the ultrasonographic features of the cyst in the prenatal period | up to 100 weeks | Description of the cohort of fetuses prenatally diagnosed with suspected ovarian cyst |
| Type of cyst on histologic examination in case of surgery | Up to 100 weeks | \- mode and type of surgery Description of the cohort of fetuses prenatally diagnosed with suspected ovarian cyst |
| Mode and type of surgery | Up to 100 weeks | Description of the cohort of fetuses prenatally diagnosed with suspected ovarian cyst |
Countries
Italy
Outcome results
None listed