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Preventing Medication Dispensing Errors in Pharmacy Practice with Interpretable Machine Intelligence: Wave 2

Preventing Medication Dispensing Errors in Pharmacy Practice with Interpretable Machine Intelligence: Wave 2

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06795477
Enrollment
30
Registered
2025-01-28
Start date
2023-02-01
Completion date
2023-05-12
Last updated
2025-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Machine Intelligence in the Pharmacy

Brief summary

Pharmacists currently perform an independent double-check to identify drug-selection errors before they can reach the patient. However, the use of machine intelligence (MI) to support this cognitive decision-making work by pharmacists does not exist in practice. This research is being conducted to examine the effectiveness machine intelligence (MI) advice on to determine if its impact on pharmacists' work performance and cognitive demand.

Interventions

BEHAVIORALNo MI Help

Participants will complete the medication verification task without any MI help

BEHAVIORALInterpretable MI

Participants receive interpretable machine intelligence assistance to complete the medication verification tasks.

BEHAVIORALUninterpretable MI

Participants receive uninterpretable (i.e., black-box) machine intelligence assistance to complete the medication verification tasks.

Sponsors

National Library of Medicine (NLM)
CollaboratorNIH
Corey Lester
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Licensed pharmacist in the United States 2. Age 18 years and older at screening 3. PC/Laptop with Microsoft Windows 10 or Mac (Macbook, iMac) with MacOS with Google Chrome or Firefox web browser installed on the device 4. Screen resolution of 1024x968 pixels or more 5. A laptop integrated webcam or USB webcam is also required for the eye tracking purpose.

Exclusion criteria

1. Eyeglasses with more than one power (bifocals, trifocals, progressives, layered lenses, or regression lenses) 2. Cataracts, intraocular implants, glaucoma, or permanently dilated pupil 3. Require a screen reader/magnifier or other assistive technology to use the computer 4. Eye surgery (e.g., corneal) 5. Eye movement or alignment abnormalities (lazy eye, strabismus, nystagmus)

Design outcomes

Primary

MeasureTime frameDescription
Cognitive effort1 day - Single study visitDifference in cognitive effort measured by duration of fixation and fixation count
Decision accuracy1 day - Single study visitDifference in detection rate measured by number of medication verification errors
Trust change1 day - Single study visitDifference in trust as measured by visual analog scale will be calculated based on AI advice accuracy. Participants will indicate their level of trust in the AI advice after every trial on a scale from 1-100, with higher scores indicating greater levels of trust.

Secondary

MeasureTime frameDescription
Reaction time1 day - Single study visitDifference in task time measured by the number of seconds from starting the task to accepting or rejecting a medication image

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 5, 2026