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Post Operative Sensitivity of MTA Obturation

Effects of Three Different Root Canal Filling Materials Used in Single-Session Root Canal Treatment on Postoperative Pain: A Randomized Clinical Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06795282
Enrollment
54
Registered
2025-01-28
Start date
2025-01-30
Completion date
2025-12-15
Last updated
2026-01-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Pulp Disease, Endodontically Treated Teeth, Endodontic Disease

Keywords

MTA, Post-op pain, Epoxy resin sealer, putty MTA

Brief summary

The aim of this study was to investigate the difference in postoperative pain caused by different root canal sealers in patients with irreversible pulpitis symptoms and no apical lesions.

Interventions

DRUGMTA

MTA is primarily composed of tricalcium silicate, dicalcium silicate, bismuth oxide (for radiopacity), and small amounts of calcium sulfate. MTA is highly biocompatible, making it suitable for use in the root canal system and areas in close contact with tissues.

Sponsors

TC Erciyes University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* asymptomatic tooth with delayed positive response to thermal tests and electric pulp tests * large pulp perforation during caries removal, * inflamed pulp in which bleeding could not be controlled within 5 min, * periodontally healthy mature mandibular first or second molar tooth.

Exclusion criteria

* patients if they were diabetic, immunocompromised, pregnant, * had a positive history of antibiotic use during the past 1 month, * required antibiotic prophylaxis * used analgesic within 7 days prior to the beginning of treatment, * were allergic to the materials used during root canal treatment, * if the bleeding could be controlled within 5 min and vital pulp treatment could be performed, * the tooth had negative response to vitality tests and/or was symptomatic, * had an associated periapical lesion visible on a radiograph, * needed a post-core or was planned to serve as prosthetic support, * had a calcified root canal and internal or external root resorption, * had tooth with open apex * mandibular third molars

Design outcomes

Primary

MeasureTime frameDescription
7-day postoperative pain after root canal treatment7 daysAt the end of the visit, patients were educated to record their postoperative pain level by assigning a number between 0 and 10 using the numerical rating scale (NRS) chart. They were categorized into four: 0=no pain, 1-3=mild pain, 4-6=moderate pain, and 7-10=severe pain. The patients were asked to record their pain level preoperatively, at 6, 12, and 24 h, and daily for up to 7 days, and return it to he investigators at a specific time.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 9, 2026