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Study of the Safety and Efficacy of Moxidectin Tablets for the Reduction of Demodex Eyelash Infestation

A Single-center, Investigator-masked, Randomized, Placebo-controlled, Investigator-initiated Study of the Safety and Efficacy of Moxidectin Tablets for the Reduction of Demodex Eyelash Infestation.

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06795165
Enrollment
24
Registered
2025-01-27
Start date
2025-02-02
Completion date
2025-06-15
Last updated
2025-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blepharitis

Keywords

blepharitis, demodex

Brief summary

A Single-Center, Investigator-Masked, Randomized, Placebo-Controlled, Investigator Initiated Study of the Safety and Efficacy of Moxidectin Tablets for the Reduction of Demodex Eyelash Infestation

Interventions

DRUGMoxidectin 2 MG Oral Tablet

active medication

DRUGPlacebo

placebo pills

Sponsors

Eye Research Foundation, Inc.
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

\- Active blepharitis with collarettes

Exclusion criteria

* Other clinically significant eye disease

Design outcomes

Primary

MeasureTime frameDescription
Collarette count6 weelsCollarette Count

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026