Mycoplasma Genitalium Infection, Sexually Transmitted Infection (STI)
Conditions
Keywords
Mycoplasma genitalium, Chlamydia trachomatis, Neisseria gonorrhoeae, men who have sex with men
Brief summary
Objective: To assess the burden and the transmission dynamics of Mycoplasma genitalium (MG) infection in men who have sex with men in Hong Kong. Design and setting: involving a) a cross-sectional study (completion of an online self-administered survey, followed by self-sampling for testing in the laboratory, and performance of HIV self-test); b) a mathematical modelling study to simulate the transmission dynamics of MG infection and resistant MG infection and compare the impacts of test-and-treat strategies. Participants: Around 920 men who have sex with men would be recruited
Detailed description
Cross-sectional study: A total of 920 men who have sex with men aged 18 or above and normally living in Hong Kong would be recruited. Eligible participants would be asked to complete a self-administered online survey, submit self-collected urine specimen and rectal swabs for Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium testing in the laboratory, and submit HIV self-test results. Mathematical modelling study: A compartmental model would be constructed to simulate the transmission dynamics of MG infection and resistant MG infection, and analyse the impact of different test-and-treat strategies.
Interventions
None listed
Sponsors
Chinese University of Hong Kong
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* men who have sex with men aged 18 or above, normally living in Hong Kong, and could communicate in written and spoken English or Chinese
Exclusion criteria
* cannot provide consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| prevalence of MG infection | 1 year | detection of MG infections in self-collected samples divided by the total number of samples collected |
| prevalence of MG resistance mutations | 1 year | detection of MG resistance mutations macrolide/fluoroquinolone in MG positive samples divided by the total number of MG positive samples |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| prevalence of CT infection | 1 year | detection of CT infections in self-collected samples divided by the total number of samples collected |
| prevalence of NG infection | 1 year | detection of NG infections in self-collected samples divided by the total number of samples collected |
| co-infection of STIs | 1 year | number of co-infection of HIV, CT, NG, and/or MG |
| history of STI and HIV testing | ever | number of self-reported history of STI and/or HIV testing at survey |
Countries
Hong Kong
Outcome results
None listed