Ultrasonography
Conditions
Brief summary
The goal of this observational study is to evaluate the validity and reliability of ultrasound echo intensity (EI) as a diagnostic tool for assessing muscle quality in children aged 10-14 years, including normal-weight, obese, and trained young athletes. The main questions it aims to answer are: Can EI reliably and accurately measure muscle quality in children when validated against gold-standard techniques like DXA and isokinetic dynamometry? What are the age-, sex-, and fitness-specific benchmarks for EI to differentiate between normal and pathological muscle quality?
Interventions
None listed
Sponsors
Charles University, Czech Republic
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
10 Years to 14 Years
Healthy volunteers
Yes
Inclusion criteria
• Generally healthy children
Exclusion criteria
* Acute illnesses * Chronic or acute diseases of the endocrine or musculoskeletal systems * Post-traumatic conditions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Echo intensity of the vastus lateralis (VL) and rectus femoris (RF) muscles | Through study completion, an average of 1 year | Echo intensity will be measured by greyscale analysis derivered from ultrasound imaging. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Skeletal Muscle Mass | Through study completion, an average of 1 year | Measured using DXA (Horizon DXA platform, Hologic) |
| Muscle Strength | Through study completion, an average of 1 year | Assessed via isokinetic and isometric knee extensor strength using a Humac Norm isokinetic dynamometer |
Countries
Czechia
Contacts
Primary ContactMichal Steffl, PhD
Outcome results
None listed