Schizophrenia
Conditions
Keywords
Cognitive difficulties
Brief summary
Existing treatment for individuals with psychosis primarily targets positive symptoms but has only modest effects on cognition and negative symptoms. Cognitive strategy training shows promising effects in reducing negative symptoms and increasing activity initiation in individuals with schizophrenia. This project aims to investigate the effect of the Perceive, Recall, Plan and Perform (PRPP) intervention in promoting effective use of cognitive strategies for adults with schizophrenia in performing their daily activities. Twenty-seven individuals with schizophrenia will be recruited from Sykehuset Innlandet (Innlandet Hospital Trust) and assessed using PRPP prior to an eight-session PRPP intervention. Re-assessment will be conducted after the intervention, as well as at 3 and 6 months, to evaluate the long-term effects of the intervention. A single-case design will be used to investigate the intervention's effects. The primary outcome measure will be the PRPP assessment, and the secondary outcome measure will be the Goal Attainment Scale (GAS). Generalization measures will be used to evaluate whether there are relevant changes beyond the primary and secondary goals.
Interventions
The PRPP is a standardized system which determines the impact of information processing on performance of everyday activities. It is a method for assessment of performance mastery, and efficient use of cognitive strategies, as well as a model of intervention to train mastery and cognitive strategy use, in everyday activities. The PRPP assess task performance mastery, as well as cognitive strategy application
Sponsors
Study design
Masking description
We plan for the assessor to be blinded when scoring the PRPP assessment. Therefore, one occupational therapist will conduct the assessments before and after the intervention, and another will provide the intervention for the participants. Additionally, to monitor observer drift , a third occupational therapist (the PhD candidate and the main supervisor) will be blinded to the phases and score 20 % of the PRPP assessments.
Intervention model description
Perceive, Recall, Plan and Perform (PRPP) intervention, to promote effective use of cognitive strategies for adults with schizophrenia when performing everyday activities in a real-world context. 27 persons with cognitive impairment due to schizophrenia will be included and provided the PRPP intervention in eight sessions. A single case experimental design with multiple baselines will be used to investigate the effectiveness of the PRPP intervention.
Eligibility
Inclusion criteria
* DSM-5 diagnosis of schizophrenia, understand and speak Norwegian, live in their own community context, but are patients in Sykehuset Innlandet ( Innlandet Hospital Trust), either as outpatients or on discharge from inpatient care, a subjective experience of functional impairment and/or cognitive difficulties identified in an initial interview, and a stable state without any major medication change for at least two months before inclusion
Exclusion criteria
* Major physical disability, a current substance abuse problem, and cognitive deficits of organic origin or mental retardation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| PRPP assessment | Assesments just after the intervention, as well as at 3 and 6 months | Effective use of cognitive strategies in performing their daily activities |
Secondary
| Measure | Time frame |
|---|---|
| Goal Attainment Scale | Assesments just after the intervention, as well as at 3 and 6 months |
| Health of the Nation Outcome Scale | Assesments just after the intervention, as well as at 3 and 6 months |
| Social Functioning Scale | Assesments just after the intervention, as well as at 3 and 6 months |
| Questionnaire about the Process of Recovery | Assesments just after the intervention, as well as at 3 and 6 months |