Congenital Heart Disease (CHD)
Conditions
Brief summary
Vitamin C will be given before admission in the immediate preoperative preceding 7 days (the dose 30 -45 mg per day ) in oral drops preparations Inflammatory markers including CRP , TLC ,PNI , GPS NLR will be checked on admission and on discharge and compared between cases and controls Hospital length stay will also be compared between the two groups
Interventions
OTHERVitamin C
Vitamin C will be given before admission in the immediate preoperative preceding 7 days (the dose 30 -45 mg per day ) in oral drops preparations Inflammatory markers including CRP , TLC ,PNI , GPS NLR will be checked on admission and on discharge and compared between cases and controls Hospital length stay will also be compared between the two groups
OTHERPlacebo
Placebo will be given before admission in the immediate preoperative preceding 7 days (the dose 30 -45 mg per day ) in oral drops preparations Inflammatory markers including CRP , TLC ,PNI , GPS NLR will be checked on admission and on discharge and compared between cases and controls
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
No minimum to 7 Years
Healthy volunteers
No
Inclusion criteria
* Children in the first two years who will be for corrective surgery for heart diseases congenital heart diseases * Pediatric patients whose parents or caregivers agree to be enrolled in the study. * Risk Adjustment for Congenital Heart Surgery -1 (RACHS-1) for Evaluation of Mortality in Children Undergoing Cardiac Surgery : the first two categories (Thiagarajan and C. Laussen 2015)
Exclusion criteria
* Pediatric patients with associated comorbid conditions.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The improvemnents of Ejection Fraction between the two groups | 7-10 days | Each group wil be evaluated for the eiection fraction before and after the operation and the improvement will be compared |
Contacts
Primary ContactHoda Atef Abdelsattar Ibrahim
Outcome results
None listed