Comparison of the Clinical Performance of High Strength Hybrid Ceramic Indirect Restorations Cemented on Endodontically Treated Teeth Using Bioactive Versus Conventional Self Adhesive Resin Cements.

Clinical Performance of CAD/CAM Hard Hybrid Ceramic Overlays on Endodontically Treated Molars Using Bioactive Versus Conventional Self-Adhesive Resin Cement: Two-Year Randomized Clinical Trial

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06787469

Enrollment

Registered

2025-01-22

Start date

2025-06-23

Completion date

2027-01-01

Last updated

2025-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endodontically Treated Molar

Keywords

Resin Cement, SHOFU, Bioactive Resin Cement, SPRG, S-PRG, Endodontically treated teeth, BeautiLink SA

Brief summary

Cementation of indirect restoration is a determinant of the success or failure of the fabricated restoration and consequentially the entire tooth. While there are numerous commercially available resin cements in the dental market, not all have been sufficiently assessed with significant follow up periods to clinically determine their success or failure. As such, this research will be conducted to elucidate if there is a viability to the cementation of indirect hybrid ceramic blocks over endodontically treated teeth using bioactive self-adhesive resin cement and determining whether it provides a clinical advantage and improved restoration serviceability in the oral cavity.

Interventions

OTHERResin Cement

Bioactive self adhesive resin cement (SHOFU BeautiLink) used to cement indirect restorations to endodontically treated molars.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Intervention model description

This study will be conducted on the form of a randomized controlled, unicenter, clustered two-arm superiority trial with a 1:1 allocation.

Eligibility

Sex/Gender

ALL

Age

21 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Patient Related Criteria: * Adult patients (age: 21-50 years) of both genders. * Able to tolerate necessary restorative procedures. * Willing to sign the informed consent. * Accepts the follow-up period. Tooth Related Criteria: * Endodontically treated first and second permanent molars. * Access cavities with one missing proximal wall i.e. Occluso-mesial/distal cavities * Patients with proper oral hygiene

Exclusion criteria

* Endodontically treated anterior, premolar and third molar teeth * Badly broken-down teeth * Hopelessly carious/destructed teeth necessitating extraction * Mobile teeth, indicating periodontal disease or trauma. * External or internal resorption. * Cervical carious lesions * Medically compromised patients * Patients with known allergies to Latex and/or resinous material

Design outcomes

Primary

Measure	Time frame
Modified USPHS Criteria	2 years

Contacts

Primary ContactAhmed N Shalaby, Masters Restorative Dentistry

ahmad.shalaby@dentistry.cu.edu.eg+201014850792

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026