Oral Cancer
Conditions
Keywords
Artificial intelligence, Oral cancer, Maximum interincisal opening, Physical function, Prehabilitation, Physiotherapy
Brief summary
This study examines the effects of AI-based physiotherapy on oral function, shoulder function, whole-body physical function, and quality of life in oral cancer patients. One hundred patients will be recruited before surgery, chemotherapy, or radiotherapy and randomly assigned to an experimental group receiving 12 weeks of AI-guided physiotherapy or a control group receiving usual care. Both groups will perform jaw, neck, and shoulder exercises, with the experimental group using a mobile app to monitor progress. Assessments at baseline, pre-intervention, and 3 months post-intervention will measure maximal in the maximum interincisal opening (MIO), joint range of motion (ROM), pain, endurance (e.g., 6-minute walk test), upper extremity function, and quality of life.
Detailed description
This study examines the effects of AI-based physiotherapy on oral function (e.g., mouth opening), shoulder function (e.g., shoulder joint range of motion and upper extremity function), whole-body physical function (e.g., 6-minute walk test), and health-related quality of life. 100 newly diagnosed oral cancer patients will be recruited before surgery, chemotherapy, or radiotherapy and randomly assigned to two groups. The experimental group will receive AI-based physiotherapy for 12 weeks, including postural correction exercises guided by AI technology, while the control group will receive usual care. Both groups will perform jaw, neck, and shoulder exercises, with the experimental group using a mobile app to monitor progress and record their exercise diaries. Assessments at baseline, pre-intervention, and 3 months post-intervention will measure the maximum interincisal opening (MIO), joint range of motion (ROM), pain, endurance, and upper extremity function using the Disabilities of the Arm, Shoulder, and Hand (DASH) scores, and quality of life using the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30).
Interventions
BEHAVIORALAI-based physiotherapy
jaw, neck, shoulder ROM exercises, and scapular-focused exercises guided by AI technology, 30 minutes of intervention, once a week, and a total of 12 weeks
BEHAVIORALConventional physiotherapy
jaw, neck, shoulder ROM exercises, and scapular-focused exercises, 30 minutes of intervention, once a week, and a total of 12 weeks
BEHAVIORALScar management
scar massage and jaw-mobilizing exercises combined with devices or depressors
Sponsors
National Taiwan University Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Newly diagnosed oral cancer patients who are scheduled to receive cancer-related treatments (e.g., oral cancer surgery, radiotherapy, chemotherapy, or chemoradiotherapy). * Age between 20 and 65 years.
Exclusion criteria
* Could not communicate. * Had any disorder that could influence movement performance.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in maximal mouth opening | baseline, pre-intervention, 3-months post-intervention | Average maximal mouth opening measured 3 times in mm |
| Change from baseline in shoulder joint range of motion | baseline, pre-intervention, 3-months post-intervention | Average range of motion of shoulder abduction measured 3 times in degrees |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in function on Disabilities of the Arm, Shoulder, and Hand outcome questionnaire | baseline, pre-intervention, 3-months post-intervention | A total scale from 1 to 100. Higher scores indicate greater disability. |
| Change from baseline in health-related function on EORTC QLQ-C30 questionnaire | baseline, pre-intervention, 3-months post-intervention | A total scale from 1 to 100. Higher scores indicate greater function. |
| Change from baseline in whole-body physical function on 6-minute walk test | baseline, pre-intervention, 3-months post-intervention | Walking distance measured in meters. |
| Change from baseline in shoulder pain | baseline, pre-intervention, 3-months post-intervention | Visual analog scale from 0 to 10. Higher scores indicate most pain. |
Countries
Taiwan
Contacts
CONTACTYueh-Hsia Chen, PhD
PRINCIPAL_INVESTIGATORYueh-Hsia Chen, PhD
National Taiwan University, College of Medicine
Outcome results
None listed