Optimal Positive End-Expiratory Pressure in Robotic-Assisted Thoracic Surgery Without Capnothorax

Status

Enrolling by invitation

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06784037

Enrollment

Registered

2025-01-20

Start date

2024-02-16

Completion date

2025-12-31

Last updated

2025-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical Ventilation, Positive End Expiratory Pressure (PEEP), Robotic Thoracic Surgery

Keywords

robotic lung surgery, PEEP, capnothorax

Brief summary

The aim of this study is to assess the impact on lung mechanics during robotic lung resection when no capnothorax is used.

Detailed description

Assess the improvement of oxygenation, ventilation and lung mechanics in patients ventilated with individualized PEEP without capnothorax. PEEP requirement and lung mechanics without capnothorax will be compared with a historical cohort population of robotic surgery with capnothorax.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients undergoing uniportal robotic lung resection under no capnothorax

Exclusion criteria

* Refusal to participate * Contraindications to recruitment maneuvers

Design outcomes

Primary

Measure	Time frame	Description
Respiratory airway pressures	During intra-operative mechanical ventilation (4 hours)	Respiratory airway pressures (peak pressure, plateau pressure and PEEP in cmH2O)
Respiratory rate	During intra-operative mechanical ventilation (4 hours)	Respiratory rate (in cycles per minute)
Respiratory system compliance	During intra-operative mechanical ventilation (4 hours)	Respiratory pressures measurement will be combined to obtain respiratory system compliance. Respiratory system compliance = (plateau pressure-PEEP) / respiratory tidal volume (expressed in cmH2O/mL)

Secondary

Measure	Time frame	Description
Arterial blood gas parameters: sodium bicarbonate	During intra-operative mechanical ventilation (4 hours)	Arterial blood sample sodium bicarbonate concentration (in mmol/L)
Arterial blood gas parameters: pO2	During intra-operative mechanical ventilation (4 hours)	pO2 in mmHg in arterial blood gas sample
Arterial blood gas parameters: base excess	During intra-operative mechanical ventilation (4 hours)	Base excess in arterial blood gas samples in mEq/L
Arterial blood gas parameters: pCO2	During intra-operative mechanical ventilation (4 hours)	pCO2 in mmHg in arterial blood gas sample
Arterial blood gas parameters: pH	During intra-operative mechanical ventilation (4 hours)	pH of arterial blood gas samples (no unit can be applied)

Countries

Spain

Outcome results