Acute Lobar Haematoma, Cerebral Hemorrhage
Conditions
Keywords
Cerebral haemorrhage, MRI
Brief summary
Cerebral haemorrhage represents a minority of acute vascular syndromes (less frequent than ischemic stroke, at around 20%), but with a therapeutic impasse, having no specific treatment. Arterial contrast ("spot sign") within the hematoma has been described in CT scans as a risk factor for further enlargement and poor prognosis. An equivalent marker has also been described in gadolinium-enhanced MRI. By studying the radiological appearance of gadolinium "spot signs" on MRI, which has better parenchymal resolution, the researchers propose to retrace the phenomenology of the acute phase of cerebral hemorrhage in order to better estimate the risk of radiological aggravation by subgroup, which could serve as a target population for future therapeutic trials.
Interventions
None, pure observational study
Sponsors
Centre Hospitalier Universitaire de Nīmes
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with acute cerebral hematomas from existing databases of cerebral amyloid angiopathy and hypertensive microangiopathy managed at Nîmes University Hospital; * Patients who have undergone a follow-up cerebral CT scan in the event of worsening or for follow-up.
Exclusion criteria
* Patient refusing to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Presence of spot sign on gadolinium MRI | baseline | Presence of spot sign on gadolinium MRI (Yes/No) |
| Morphologic description of gadolinium MRI spot sign | baseline | morphological (shape, location within the hematoma) description of spot signs on brain MRI |
| Quantitative description of gadolinium MRI spot sign | baseline | Quantitative (number and categorial) description of spot signs on brain MRI |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| association of spot sign with hematoma expansion on follow-up CT | Baseline | association of spot sign with hematoma expansion on follow-up CT(Yes/No) |
| Association with the underlaying pathology | Baseline | Association with the underlaying pathology as identified by the authors (Yes/No) |
Countries
France
Contacts
CONTACTTeodora PARVU
STUDY_DIRECTORAnissa MEGZARI
Centre Hospitalier Universitaire de Nīmes
Outcome results
None listed