Frequency and Predictors of Recurrent SBP in Cirrhotic Patients in Al Rajhi University Hospital

Frequency and Predictors of Recurrent Spontaneous Bacterial Peritonitis in Cirrhotic Patients in Al Rajhi University Hospital

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06778616

Enrollment

101

Registered

2025-01-16

Start date

2025-02-28

Completion date

2025-11-30

Last updated

2025-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spontaneous Bacterial Peritonitis

Brief summary

* Assess the frequency of recurrent SBP in ascitic cirrhotic patients. * Determine the predictive factors of recurrence after the first episode of SBP in ascitic cirrhotic patients

Detailed description

Spontaneous bacterial peritonitis (SBP) is a common complication in cirrhotic patients. The prevalence of SBP in hospitalized patients and the mortality rate were reported to be 10%-30% and 30%-50%, respectively. SBP has been considered a life-threatening infection that requires a prompt diagnosis and treatment.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 80 Years

Healthy volunteers

Inclusion criteria

* Any cirrhotic patient above the age of 18 years old of both sexes, having a first episode of SBP will be included in our study. 1. The diagnosis of cirrhosis was based on clinical manifestation (ascites, splenomegaly, lower limb edema and/or esophageal varices by upper gastrointestinal endoscopy), laboratory findings and radiological (abdominal ultrasonography), or liver histology. 2. The diagnosis of SBP was based on a neutrophil cell count of 250 cell or more per mm3 with or without culture positivity of ascitic fluid, in the absence of hemorrhagic ascites and secondary peritonitis.

Exclusion criteria

* Any patient with one or more of the following criteria will be excluded: 1. Patients with bacterial ascites defined by a positive culture of ascitic fluid associated with a neutrophil cell count less than 250 cell per mm3 in the ascitic fluid. 2. Patients presenting with empyema or bacterial peritonitis secondary to an intra-abdominal organ perforation or surgical operation

Design outcomes

Primary

Measure	Time frame	Description
Frequency and Predictors of Recurrent Spontaneous Bacterial Peritonitis in Cirrhotic Patients in Al Rajhi University Hospital.	One year	Determine the frequency of recurrent SBP after its management within one year

Secondary

Measure	Time frame	Description
Predictors of recurrent SBP	One year	Determining risk factors of recurrent SBP

Countries

Egypt

Contacts

Primary ContactAsmaa M Hussein, MSc

asmaamoussa299@gamil.com00201070041233

Backup ContactMarwa A Ahmed, MD

Marwamakhlof088@gmail.com00201155544090

Outcome results