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Evaluation of the Efficacy of the ALLYANE Procedure in the Treatment of Central Motor Inhibition

Evaluation of the Efficacy of the ALLYANE Procedure in the Treatment of Central Motor Inhibition Immediately After Knee Sprain as an Adjunct to Conventional Treatment.

Status
Enrolling by invitation
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06774157
Enrollment
120
Registered
2025-01-14
Start date
2024-01-15
Completion date
2026-12-20
Last updated
2025-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthrogenic Muscle Inhibition, Arthrogenic Muscle Inhibitions

Keywords

AMI, ALLYANE, low frequency sounds, motor imagery

Brief summary

The goal of this clinical study is to determine the effectiveness of restoring muscle strength in the management of motor inhibition when complemented by the ALLYANE process (neuro-motor reprogramming) compared to a standard management approach. The main questions it aims to answer are: * Does the ALLYANE process lead to greater muscle strength gains compared to standard care? * Is there a functional benefit when standard management is complemented by the ALLYANE process? The investigators will compare the group receiving standard care complemented by ALLYANE to a group receiving only standard care to evaluate if the ALLYANE process provides additional effects. Participants will: * Undergo assessments of muscle strength. * Receive either standard management or standard management with ALLYANE. * Complete functional evaluations before and after treatment.

Detailed description

This study aims to evaluate the effectiveness of motor inhibition management using two different approaches: standard management alone and standard management supplemented by the ALLYANE neuro-motor reprogramming process. To ensure robust and reliable results, the study proposes enrolling a total of 120 patients, divided into two groups of 60 patients each.

Interventions

OTHERA session combining motor imagery and listening to low frequency sounds

Prospective study of the efficacy of the Allyane procedure after knee sprain

Active extension (e.g. by lateral raising of the quadriceps, strengthening of the quadriceps) quadriceps)

Sponsors

Orthopedic Center Santy, Lyon, France
CollaboratorUNKNOWN
Laboratoire Interuniversitaire de Biologie de la Motricité
CollaboratorOTHER
Allyane
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
No

Inclusion criteria

* Men and women aged 18 to 35 years * No neurological history * Have had a primary knee sprain * Present with VMO lateralisation with or without the presence of flessum * Quadricipital weakness between the healthy and injured limb of 50% or more as measured by a portable dynamometer * Member of a social security scheme

Exclusion criteria

* Recurrent sprain * Bilateral sprain * Persons under guardianship, trusteeship or any other measure depriving them of their rights or liberty, and adults protected by law. * Persons who do not understand French * Knee trauma other than sprain *

Design outcomes

Primary

MeasureTime frameDescription
Muscle activityBefore and 3 weeks after conventional therapyElectromyography (EMG) during maximal voluntary isometric contraction of leg extension.

Secondary

MeasureTime frameDescription
StrengthBefore and 3 weeks after conventional therapyDynamometer during maximal voluntary isometric contraction of leg extension.

Other

MeasureTime frameDescription
Lysholm QuestionnaireBefore and 3 weeks after conventional therapy.A self-administered survey used to evaluate knee function and stability.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026