Diabetes, Diabetic Foot Disease, Diabetic Foot Ulcer (DFU)
Conditions
Brief summary
The purpose of this study was to retrospectively analyze the wound condition, limb condition, ulcer recurrence and cardiovascular and mortality of patients with diabetic foot ulcer after admission to our hospital from 2009 to 2014, so as to understand the changes in the condition of patients with diabetic foot ulcer after treatment, provide evidence for the treatment of diabetic foot, and clarify the risk of diagnosis and treatment of diabetic foot.
Detailed description
Diabetic foot ulcer (DFU) is one of the most common and serious complications in patients with diabetes. Due to its high incidence and complicated treatment process, DFU often has a significant impact on patients' quality of life. In order to gain an in-depth understanding of the wound changes of diabetic foot patients after admission, this study aims to systematically analyze the data of the database of diabetic foot patients in Ruijin Hospital, analyze the wound healing, ulcer recurrence and limb changes of diabetic foot patients, including amputation and other conditions, and then further determine the main factors affecting diabetic foot ulcer healing. Guide clinicians to develop more effective treatment plans; Provide data support to help optimize the treatment flow of diabetic foot and reduce length of stay and recurrence rates; To improve the overall treatment effect of diabetic foot patients and improve their quality of life. Objective: 1. The wound condition, limb condition, ulcer recurrence and cardiovascular and mortality changes of patients with diabetic foot after treatment were analyzed to clarify the risk of diagnosis and treatment of the disease and provide evidence for the treatment of diabetic foot. 2. To assess the progress of wound healing in patients with diabetic foot after admission to hospital and identify key factors that promote or delay healing. 3. By comparing the effects of different treatment methods (such as drug therapy, surgical intervention, adjuvant therapy, etc.), the most suitable treatment strategy is found. 4. The incidence of complications during and after treatment was analyzed, and effective management strategies were discussed. Methods:Through systematic analysis of the data from the database of diabetic foot patients in Ruijin Hospital, the wound healing, ulcer recurrence and limb changes of diabetic foot patients, including amputation, were analyzed, and then the main factors affecting diabetic foot ulcer healing were further determined.
Interventions
OTHERLevel of blood sugar control (e.g., hemoglobin A1C), severity of infection, blood supply status, and other complications (e.g., peripheral neuropathy)
Level of blood sugar control (e.g., hemoglobin A1C), severity of infection, blood supply status, and other complications (e.g., peripheral neuropathy)
Sponsors
Shanghai Jiao Tong University School of Medicine
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age ≥ 18 years old 2. Gender: males and females 3. Patients diagnosed with diabetic foot ulcers (including those on the Wagner scale 0-5) 4. Receive inpatient treatment during the designated study period
Exclusion criteria
1. Patients with severe systemic disease (such as end-stage renal disease, advanced cancer, etc.) may have influenced the study results 2. Patients unable to complete follow-up or with incomplete data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ulcer healing rate in diabetic foot ulcers | Look at the last 10 years retrospectively |
| Ulcer recurrence rate in diabetic foot ulcer patients | Look at the last 10 years retrospectively |
| Amputation rate in diabetic foot ulcers | Look at the last 10 years retrospectively |
| Mortality of diabetic foot ulcers | Look at the last 10 years retrospectively |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Key independent factors that affect wound healing | Look at the last 10 years retrospectively | Through in-depth analysis of the diabetic foot ulcer patient database, the study is expected to identify key independent factors that affect wound healing, including the patient's level of blood sugar control (such as hemoglobin A1C), severity of infection, blood supply status, and other complications (such as peripheral neuropathy and vascular disease). |
Countries
China
Outcome results
None listed