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Speed of Glucose Absorption During Exercise

The Need for Speed: Comparing the Speed of Glucose Absorption During Repeated Sprint Cycling

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06768333
Enrollment
10
Registered
2025-01-10
Start date
2025-01-06
Completion date
2025-02-05
Last updated
2025-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy, Healthy Nutrition

Brief summary

The purpose of this study is to look at how fast commercially available supplements containing carbohydrates can get into the bloodstream during repeated sprint cycles. This will build from a pervious study where the investigators tested these supplements on healthy participants during a resting oral glucose tolerance trial. The investigators will be testing three supplements, namely Voom Pocket Rocket, SIS Go Isotonic Energy Gel, and Maurten Gel 160. Each participant will complete all three conditions, consuming one of each supplement at random per condition. The study requires participation from male and female runners, cyclists and triathletes who are aged between 18-40. Each visit will take approximately 1 hour, and three experimental visits per participant. The study will involve frequent blood sampling and the continuous monitoring of gas exchange (oxygen/carbon dioxide). Blood sampling via cannulation will be used to analyse the lactate, glucose, and electrolyte content of the blood. Gas exchange will measure the oxygen breathed in and carbon dioxide breathed out throughout the exercise. The investigators plan to carry out the study on 10 participants who will be a mix of male and female runners, cyclists and triathletes.

Interventions

Participants will be required to consume 45 grams (in carbohydrates) of the Voom Pocket Rocket Electro Energy on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

DIETARY_SUPPLEMENT45 grams Maurten Gel 160

Participants will be required to consume 45 grams (in carbohydrates) of the Maurten Gel 160 on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

Participants will be required to consume 45 grams (in carbohydrates) of the SIS Go Isotonic Energy Gel on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

Sponsors

Lancaster University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Masking description

Both the participants and investigators will be blinded to what supplement they are consuming on each visit. Each supplement will taste the same, and be placed into identical packaging, and be randomly labelled (e.g., A, B, C). This will be done to avoid potential bias.

Intervention model description

This will be a double-blind randomised crossover design. There will be 1 group of participants who will complete all three conditions at random: Condition 1 - consume Voom Pocket Rocket. Condition 2 - consume SIS Isotonic Energy Gel. Condition 3 - consume Maurten Gel 160. Participants will consume each product 35 minutes before starting exercise. All participants will undergo the same exercise - 5 repeated sprint cycling (cycling against 0.075 kg/ kg body mass) intervals of 15 seconds interspersed with 3 minutes of active recovery. All participants will have the same measures taken - blood sampling for blood glucose, blood lactate, and electrolytes at the end of each sprint and period of active recovery, and monitoring of gas exchange throughout the exercise.

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Aged between 18-40 years * Male or female * Tier 2 athletes - local level representation, training \ 3 times per week, training with a purpose to compete, identify with a specific sport, limited skill development (McKay et al., 2021)

Exclusion criteria

* Allergies to any listed ingredients on any supplements. * Diabetes (type 1 or 2) * Any medical conditions * Smokers * Any injury that would prevent them from exercising * Anyone using drugs or medication (not including contraception) * Anyone consuming alcohol within 24 hours of the study * Exercise must be restricted within 24 hours of the study * Caffeine must not be consumed within 24 hours of testing as it can significantly enhance carbohydrate oxidation rates (Yeo et al., 2005) * Diets including high-carbohydrate-low-fat (HCLF), low-carbohydrate-high-fat (LCHF), ketogenic, and/or glycogen manipulation diets (Rauch et al., 2022)

Design outcomes

Primary

MeasureTime frameDescription
Blood GlucoseBlood glucose measures will be taken 35 minutes after consuming the supplement(s) (baseline), after the 3 minute warmup, and then after every 15 second sprint and every 3 minute period of active recoveryFrequent blood sampling for blood glucose (1ml after every stage of both sprint cycling and active recovery) followed by analysis in the Biosen Analyser
Blood LactateBlood lactate measures will be taken 35 minutes after consuming the supplement(s) (baseline), after the 3 minute warmup, and then after every 15 second sprint and every 3 minute period of active recoveryFrequent blood sampling for blood lactate (1ml after every stage of both sprint cycling and active recovery) followed by analysis in the Biosen Analyser
Gas ExchangeGas exchange will be measured continuously throughout the 20 minutes of exercise, starting at the warmupGas exchange measured throughout each 20 minute exercise via a Cortex Metalyzer

Secondary

MeasureTime frameDescription
Blood electrolyte contentBlood electrolyte measures will be taken 35 minutes after consuming the supplement(s) (baseline), after the 3 minute warmup, and then after every 15 second sprint and every 3 minute period of active recoveryFrequent blood sampling for electrolyte concentrations of the blood (sodium, potassium, chloride, calcium) (1ml after every stage of both sprint cycling and active recovery) followed by analysis in the Biosen Analyser
Rate of Percieved exertion (RPE)RPE will be measured at the end of the warmup and the end of the final sprint stageParticipants will report their RPE using the Borg Scale to report how hard they are finding the exercise. This will be done after the warm-up and after the final sprint.
Gastrointestinal (GI) Discomfort QuestionnaireGI Discomfort will be measured 5 minutes before and 5 minutes after exerciseParticipants will complete a GI discomfort questionnaire 5 minutes before starting exercise and at the end of exercise

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026