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Investigation of Upper Extremity Functions in Patients With Rheumatoid Arthritis

Investigation of Upper Extremity Exercise Capacity, Hand Grip Strength and Daily Living Activities in Rheumatoid Arthritis Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06767618
Enrollment
26
Registered
2025-01-10
Start date
2025-03-25
Completion date
2026-03-25
Last updated
2026-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis

Keywords

exercise capacity, upper extremity, hand-grip strength

Brief summary

There are limited studies in the literature evaluating upper extremity functional exercise capacity, muscle functions and daily living activities in rheumatoid arthritis patients. In this context, the aim of this study was to investigate upper extremity exercise capacity, hand grip strength and daily living activities in rheumatoid arthritis patients.

Detailed description

Rheumatoid arthritis is an inflammatory autoimmune chronic and systemic disease of unknown etiology. In addition to musculoskeletal involvement, lung involvement can also be observed in patients. Lung involvement and accompanying symptoms cause deterioration of physical function, quality of life and functional capacity. In rheumatoid arthritis, dyspnea can be observed during exertion due to disease progression, drug toxicity and respiratory/cardiovascular morbidities. In patients, decreased respiratory muscle strength, respiratory functions, carbon monoxide diffusion capacity and oxygen consumption also cause decreased physical functions. It has been reported that upper extremity exercise capacity and functional performance are reduced in patients with interstitial lung disease. It is known that peripheral muscle strength is an independent determinant of exercise capacity in interstitial lung disease. Rheumatoid cachexia, characterized by decreased muscle mass and increased fat mass, is observed in rheumatoid arthritis patients. Since the patients' accessory respiratory muscles are also affected, it can negatively affect their daily life activities, especially those that use the upper extremities.

Interventions

None listed

Sponsors

Kirsehir Ahi Evran Universitesi
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

Inclusion criteria for patients with rheumatoid arthritis * Patients diagnosed with rheumatoid arthritis, * Between the ages of 18-75 years, * Patients who volunteer to participate in the study will be included in the study.

Design outcomes

Primary

MeasureTime frameDescription
Evaluation of Upper Extremity Exercise CapacityFirst day and second dayThe six minute peg board and ring test will be used to assess upper extremity exercise capacity.
Glittre Activities of Daily LivingSecond dayThe Glittre activities of Daily Living test will be used to evaluate the daily living activities of individuals.

Secondary

MeasureTime frameDescription
Hand-grip strengthFirst dayHand-grip strength will be assessed using a hand dynamometer.
Evaluation of upper extremity functional statusFirst dayThe Arm, Shoulder and Hand Disabilities Questionnaire (DASH) will be used to evaluate the upper extremity functional status of individuals. The DASH evaluates the functional status of the upper extremity subjectively according to the Likert scale. It consists of 3 sections. The questionnaire scores between 0 (no disability) and 100 (severe disability).
Evaluation of arm and shoulder muscle strength and enduranceSecond dayThe Thirty-Second Push-Up Test will be used to evaluate arm and shoulder muscle strength and endurance.

Countries

Turkey (Türkiye)

Contacts

STUDY_CHAIRBaşak KAVALCI KOL, Dr.

Kirsehir Ahi Evran Universitesi

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 14, 2026