Ramadan Fasting
Conditions
Keywords
Ramadan, Fasting, VO2max, Dietary Nitrate
Brief summary
The goal of this clinical trial is to determine if beetroot juice supplementation changes exercise performance following one week of Ramadan fasting in young, healthy adults. The main question it aims to answer is: Does daily beetroot juice supplementation change VO2 max in fasting individuals during the first week of Ramadan? Participants will: Visit the lab before the start of Ramadan and after one week of fasting If assigned to intervention group, consume daily shots of beetroot juice (70ml) during the first week of Ramadan fasting Perform maximal exercise testing on a cycle ergometer
Detailed description
Recent literature demonstrates data showing a decrease in VO2max during the first week of Ramadan fasting. This is a practice observed by millions around the world every year, where individuals abstain from food and water from sunrise to sunset, dictated by the lunar calendar. Dietary nitrate consumption has been shown to increase VO2max and exercise performance. Therefore, the primary purpose of this study is to investigate whether dietary nitrate, in the form of beetroot juice, can help mitigate the decrease in VO2 max during the first week of Ramadan fasting. 24 young healthy adults will be recruited to undergo these two visits. The first visit will assess maximal oxygen uptake to determine aerobic fitness and metabolic exercise intensity zones under non-fasting conditions. The second visit will be completed after one week of Ramadan fasting. If assigned to the intervention group, participants will consume one shot (70ml) of Blonyx - Beet It Sport Nitrate 400 beetroot juice every day. Each shot contains 400mg of nitrates. Urine Specific Gravity will be measured after each visit to assess hydration status. The intervention group will also undergo Single Blood Draws after each visit to assess nitrate concentrations before and after a week of consumption.
Interventions
DIETARY_SUPPLEMENTBeetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training
7 doses, taken daily, 70 ml shots, consumed in the morning before the start of fasting
Sponsors
University of Guelph
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Free of known cardiovascular or metabolic diseases or sleep disorders * No history of smoking (within the past 3 months) * Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+) * No prescription of chronic medications other than oral contraceptives * Able to abide by fasting protocols for all visits * Individuals who are not allergic to ultrasound gel or beetroot juice * Individuals who are not pregnant
Exclusion criteria
* Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders * Has a history of smoking (within the past 3 months) * Not ready to engage in physical activity as assessed by the PAR-Q+ * Individuals prescribed chronic medications other than oral contraceptives * Unable to abide by fasting protocols for any testing visit * Allergic to ultrasound gel or beetroot juice * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VO2 max | One--week differences between before and after 1 week of fasting, nitrate supplementation if in intervention group | Maximal Oxygen Uptakes will be assessed to analyze aerobic capacity and fitness under fasting conditions. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Nitrate Concentration levels | Comparison between blood before and after nitrate supplementation: one week | Single blood draws will be taken after each visit for the nitrate supplementation group |
Countries
Canada
Contacts
PRINCIPAL_INVESTIGATORPhillip Millar, PhD
University of Guelph
Outcome results
None listed