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Infiltration Anesthesia vs. Block Anesthesia

Effectiveness of Local Anesthetic Infiltration With Articaine 4% in Comparison to Inferior Alveolar Nerve Block With Lidocaine 2% for Mandibular 1st Molar Extraction

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06766981
Acronym
LAI
Enrollment
100
Registered
2025-01-09
Start date
2025-01-10
Completion date
2025-03-01
Last updated
2025-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Extraction

Keywords

Local Anesthesia, Inferior Dental Nerve Block, Infiltration Anesthesia

Brief summary

Checking the effectiveness of the infiltration technique of local anesthetic agent as an alternative to inferior dental nerve block during tooth extraction

Detailed description

Patients who need their Mandibular first Molar to be removed under local anaesthesia. The first group will receive 4% articaine with 1:100,000 epinephrine as lingual and buccal infiltration. In comparison, the second group will receive a conventional inferior alveolar nerve block technique with 2% lidocaine with epinephrine (1:80,000). Pain will be measured para-operatively using a verbal rating scale.

Interventions

PROCEDUREInfiltration with Articain 4%

The experimental group of patients that are diagnosed for tooth extraction of mandibular 1st. molar will undergo extraction using an infiltration technique for local anaesthesia. In contrast to the conventional group that will receive Inferior alveolar nerve block

This group will receive a conventional inferior alveolar nerve block (IANB) technique with 2% lidocaine with epinephrine (1:80,000) for tooth extraction.

Sponsors

Babylon University
CollaboratorOTHER
Sinan A. Shwailiya
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

The interventional group will undergo tooth extraction under the infiltration anaesthesia technique

Eligibility

Sex/Gender
ALL
Age
18 Years to 58 Years
Healthy volunteers
No

Inclusion criteria

* The systemic condition must be normal. * Patient has no cardiovascular, metabolic, or transmitted disease. * The patient has a Mandibular 1st. Molar tooth indicated for extraction. * The tooth is non-restorable.

Exclusion criteria

* Chronic cardiovascular condition, metabolic, or infectious disease. * Pregnant women. * The tooth is restorable.

Design outcomes

Primary

MeasureTime frameDescription
Verbal Pain Rating Scaleduring the intervention/procedure/surgeryPain during tooth extraction will be measured immediately after the procedure is completed using a verbal rating scale. The zero rate will be given when the patient feels no pain; the rating degree will increase as the pain severity becomes more severe. According to the following scale: 0 No hurt 1. Slight pain 2. Moderate pain 3. Intense pain 4. Extremely painful

Countries

Iraq

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026