Ankylosing Spondylitis (AS), Behcet's Disease, Enthesitis-related Arthritis, Giant Cell Arteritis (GCA), Nr-axSpA, Polymyalgia Rheumatica (PMR), Psoriatic Arthritis (PsA), Takayasu Arteritis (TAK)
Conditions
Brief summary
Ankylosing spondylitis, radiographically negative axial spondyloarthritis, psoriatic arthritis, polymyalgia rheumatica, Takayasu arteritis, giant cell arteritis, non-ocular Behcet's disease, and enthesitis-related arthritis are common diseases in rheumatology. Traditional anti-rheumatic drugs are less effective and have greater side effects than biological agents. At present, there has been no large-scale registration study on rheumatic autoimmune diseases such as spondyloarthritis in China. However, data such as patient characteristics, medication patterns, and patient outcome reports of different rheumatology diseases can often serve as a reference for rheumatology clinicians to reasonably select treatment methods for different patients. Therefore, a large-scale registration study is needed to fill the gap in multi-disease registration studies in rheumatology departments in China.
Interventions
None listed
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Diagnosed with rheumatic autoimmune diseases such as ankylosing spondylitis/radiologically negative axial spondyloarthritis/psoriatic arthritis/polymyalgia rheumatica/Takayasu arteritis/giant cell arteritis/ non-ocular Behcet's disease/ enthesitis-related arthritis; 2. Currently receiving or planning to receive fulvezinib treatment; 3. Can follow up according to the doctor's advice; 4. Able to understand and sign the informed consent form, understand the purpose of this study, and voluntarily participate in this study.
Exclusion criteria
1.Investigator believes will prevent the subject from following and completing the study protocol
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| European Quality of Life-5 Dimensions Questionnaire （EQ5D） score | From enrollment to the end of treatment at 12 months | European Quality of Life-5 Dimensions Questionnaire （EQ5D） score： The EQ-5D describes five dimensions: mobility, Self-Care, Usual Activities, Pain/comfort, and Anxiety/Depression, each of which contains five levels: No difficulty, a little difficulty, moderate difficulty, serious difficulty, unable to proceed/with very serious difficulty. Using a utility-value conversion table, the EQ-5D index score can be further calculated. |
| Pain VAS score | From enrollment to the end of treatment at 12 months | Pain VAS score (if applicable)：Visual Analogue Scale, The VAS score is indicated by a 10-cm-long straight line, with one end of the line indicating no pain (score 0) and the other end indicating most severe pain (score 10). Patients marked positions on this line that corresponded to their pain level, and pain was assessed by measuring the distance from the painless end to the marked point. |
Countries
China
Contacts
Primary ContactHuaxiang wu
Outcome results
None listed