Pain Management, Skin Graft Complications
Conditions
Keywords
bupivacaine, skin graft, pain, donor site, local anesthesia
Brief summary
Split Thickness Skin Graft is frequently utilized for reconstructing skin loss of various causes. Unfortunately, the donor site of the STSG has an unavoidable, annoying post-operative pain
Detailed description
The primary objective of this study was to compare the efficacy of bupivacaine hydrochloride-soaked dressing versus bupivacaine HCL subcutaneous infiltration for postoperative donor site pain control for patients undergoing STSG procedures. The patients were divided in 3 equal groups, investigated soaked dressing vs subcutaneous infiltration vs conventional dressing .
Interventions
DRUGBupivacain
to our knowledge, this study is the 1st to compare the efficacy of bupivacaine hydrochloride-soaked dressing versus subcutaneous infiltration for postoperative donor site pain control for patients undergoing STSG procedures.
Sponsors
Minia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists Physical Status classification I-II * scheduled for STSG harvested from a single thigh donor site to reconstruct skin loss post burn or trauma
Exclusion criteria
* uncooperative * refusing patient, * under immunosuppressive treatment * diabetics * lower-limb neuropathy * under corticosteroids treatment * allergy to the study drug, * STSG procedures performed under spinal anesthesia * pregnancy * had a history of opioid abuse
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| screening pain | 24 hours | Numerical rating scale (NRS), 0, 1, 2, 4, 8, 12, 18 and 24h, a tool for screening pain, often utilized to evaluate pain intensity on a 0-10 scale, where zero indicates no pain and 10 signifies the worst pain possible, in the 1st 24h postoperatively |
| frequency of analgesia and the fentanyl requirement | 24 hours | 1g of paracetamol IV was given to all patients every 8 h and if NRS \>3 in the donor site patient received 30 mg IV of ketorolac (the frequency of analgesia), if the pain still, the patient was given fentanyl 50 mcg per time (fentanyl requirement) in the three studied groups Registration of the frequency of time of 1st analgesia, frequency of analgesia (ketorolac) and the fentanyl requirement over 1st 24 h as (0, 1, 2, 4, 8, 12, 18 and 24h). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| side effects | 24 hours | recording any side effects such as convulsions and myocardial depression. |
Countries
Egypt
Outcome results
None listed