The Application of Multimodal Ultrasound Imaging in Carpal Tunnel Syndrome

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06766370

Enrollment

Registered

2025-01-09

Start date

2025-02-01

Completion date

2028-12-01

Last updated

2025-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome (CTS)

Keywords

ultrasound

Brief summary

The aim of this study is to explore the application value of multimodal ultrasound parameters in the diagnosis and treatment follow-up of Carpal Tunnel Syndrome.

Interventions

PROCEDUREUltrasound-guided nerve hydrodissection treatment

Under ultrasound guidance, a mixed solution of corticosteroids and local anesthetics is injected around the nerve, followed by release of the transverse carpal ligament.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

1. Age between 18 and 70 years; 2. Presence of sensory abnormalities and motor dysfunction in the median nerve distribution area; 3. Positive Tinel's sign or Phalen's test; 4. Neurophysiological examination consistent with mild to moderate Carpal Tunnel Syndrome.-

Exclusion criteria

1. Severe Carpal Tunnel Syndrome; 2. Concurrent rheumatic, metabolic, systemic, or other systemic diseases; 3. Concurrent cervical spondylosis or other peripheral neuropathies; 4. Wrist joint trauma, surgery, space-occupying lesions, or nerve itself with space-occupying lesions; 5. Concurrent malignant tumors or severe cardiopulmonary diseases; 6. History of previous wrist surgery or injections; 7. Pregnancy; 8. Allergy to corticosteroids or local anesthetics.-

Design outcomes

Primary

Measure	Time frame	Description
Boston Carpal Tunnel Syndrome Questionnaire ，BCTQ	1,3,6,12 months	The Boston Carpal Tunnel Score is a patient-reported questionnaire that examines symptom severity and overall functional status of patients with carpal tunnel syndrome. The Symptom Severity Scale (SSS) with 11 questions is scored on a Likert scale of 1-5 and the Functional Status Scale (FSS) with 8 questions is scored from 1-5 with 1 as no difficulty and 5 as difficult.The higher scores mean a worse outcome.

Secondary

Measure	Time frame	Description
the patient's sensory nerve conduction velocity (SNCV)	3,6,12months	SNCV in m/s
the patient's distal motor latency (DML).	3,6,12months	DML in ms

Contacts

Primary ContactNanjing Trum Tower Hospital

weijing_zhang@163.com15651890325

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026