The Study Aims to Measure the Metabolome in Melanoma Patients Using NMR Spectroscopy and Gas Chromatography and to Analyse Differences Depending on the Course of the Disease.

Measurement of the Metabolome in Melanoma Patients Using NMR Spectroscopy and Gas Chromatography.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06765850

Enrollment

3000

Registered

2025-01-09

Start date

2022-07-04

Completion date

2027-06-30

Last updated

2025-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melanoma of Skin

Keywords

Melanoma, Metabolomics, NMR

Brief summary

Prospective, single-centre study with the central question of how the metabolome from blood samples, different body fluids and tissues between patients patients with malignant melanoma in different tumour tumour stages and healthy patients and whether this is suitable for early detection of initial diagnosis, recurrence or stage shift at an early stage. The biosamples are collected in the BioBank Dresden and used for the NMR and LC-MS analyses described here. It is planned to use the biosamples for further analyses.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Current or past history of melanoma * Ongoing therapy or tumour aftercare at the Skin Cancer Centre at Dresden University Hospital

Exclusion criteria

* Refusal to participate in the study * Lack of capacity to consent

Design outcomes

Primary

Measure	Time frame	Description
Differences in metabolite concentrations	through study completion, an average of 3 years	Metabolite concentrations are measured by NMR spectroscopy and gas chromatography and compared between different subgroups.

Countries

Germany

Contacts

Primary ContactFrank Friedrich Gellrich, Dr. med.

frankfriedrich.gellrich@ukdd.de+493514582497

Outcome results