Dialysis Access Dysfunction, End-Stage Kidney Disease, End Stage Renal Disease
Conditions
Brief summary
The goal of this trial is to investigate the prognostic value of monitoring finger blood pressures (FBPs) in predicting the success of surgically created arteriovenous fistula (AVF) for patients with end stage renal disease. The main questions it aims to answer is: \- Can FBPs predict AVF maturation? Participants will undergo FBP measurements at pre-op, immediately post-op, 4 weeks and 6 weeks post-AVF creation.
Interventions
OTHERFinger Blood Pressure Measurement
Finger Blood Pressure Measurement were taken from three digits: the thumb (F1), the middle finger (F2), and the little finger (F3) from both arms.
Sponsors
Singapore General Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Participants has documented Chronic Kidney Disease (CKD), determined by Glomerular Filtration Rate (GFR) * Participant is recommended for renal replacement therapy based on clinical assessment of renal function as well as CKD staging, as documented in clinical notes. * Haemodialysis was chosen as the most appropriate renal replacement therapy * Participant is able to consent to the creation of an AVF in preparation for hemodialysis. * Participant is able to adhere to follow-up assessments of AVF maturation, if applicable.
Exclusion criteria
* Subject had a previous AVF and is now undergoing surgery for another AVF creation * Subject has amputation distal to AVF * Subject is pregnant or planning to conceive * Participants is unable to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between AVF maturation and changes in Finger Blood Pressure measurements at baseline and immediately post-op | Within 24 hours | To determine whether if there are any pattern in changes observed in FBP pre and post-creation that can be used for correlation to AVF maturation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between AVF maturation and changes in Finger Blood Pressure measurements across other timepoints | Until 6 weeks post-operation | To determine whether changes in FBP across time points (pre-op, post-op, 4 weeks and 6 weeks post-op) is correlated with AVF maturation |
Countries
Singapore
Outcome results
None listed