Wilson Disease
Conditions
Keywords
botulinum toxin type A, wilson disease
Brief summary
In order to expand the treatment of Wilson disease and improve the quality of life of patients with Wilson's disease, the clinical effect of botulinum toxin type A injection on Wilson's disease was discussed.
Interventions
DRUGBotulinum toxin type A
Local injection of botulinum toxin type A was given at the time of enrollment
Sponsors
The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
：1.Conform to the diagnosis of 2012 European Liver Study Guidelines for Diagnosis and Treatment of hepatolenticular degeneration. 2. Aged from 15 to 65 years.
Exclusion criteria
Non-Wilson's disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Unified Dystonia Rating Scale(UDRS) | 4 weeks | Unified Dystonia Rating Scale(UDRS),Higher scores mean a worse outcome. |
| Unified Wilson's Disease Rating Scale(UWDRS) | 4 weeks | Unified Wilson's Disease Rating Scale(UWDRS).Higher scores mean a worse outcome |
| Numeric Rating Scales(NRS) | 4 weeks | Numeric Rating Scales(NRS),Higher scores mean a worse outcome |
| Activity of Daily Living Scale(ADL) | 4 weeks | Activity of Daily Living Scale,Higher scores mean a better outcome. |
Countries
China
Outcome results
None listed