Hyperkyphosis, Osteoporosis, Sarcopenia, Ultrasonography
Conditions
Keywords
muscle thickness, sarcopenia, hyperkyphosis, ultrasonography
Brief summary
To determine the impact of thoracic hyperkyphosis, sarcopenia and quadriceps muscle thickness evaluated by ultrasonography (USG) on balance, fall risk and functional parameters in women with postmenopausal osteoporosis, to assess their interrelationships and to compare the clinical characteristics of sarcopenia and thoracic hyperkyphosis.
Detailed description
An observational study was conducted on patients with PMO and/or osteoporotic vertebral fractures according to WHO criteria. One hundred seventeen patients who were 50 years of age or older, with a diagnosis of PMO and/or osteoporotic vertebral fractures according to WHO criteria, who were able to ambulate without any assistive devices were included in the study. Patients with a history of neurological disease which may affect balance and proprioception, visual and vestibular disease, previous major lower extremity surgery or previous vertebra surgery were excluded. The investigators also excluded the patients with advanced heart, liver, or renal failure, stage 4 knee osteoarthritis, psychiatric disorders, and use of any medication affecting the central nervous system. Age, height, weight, body mass index (BMI), comorbidities, medications, previous surgeries, steroid use, previous fractures and the energy level of these fractures (low or high), fracture location, family history of fractures, alcohol use, smoking, menopausal age and the number of falls in a year were questioned. The FRAX algorithm was used to determine the risk of fracture. The Cobb angle of thoracic kyphosis was calculated radiographically and QFM thickness was measured from anterior thigh via ultrasonography (USG). The presence of sarcopenia was determined. Balance, fall risk and physical function were evaluated with tandem stance and gait test, Berg balance scale (BBS), Timed up and go test (TUG), hand grip strength, chair stand test (CST).
Interventions
None listed
Sponsors
Istanbul University - Cerrahpasa
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient who were 50 years of age or older, had postmenopausal osteoporosis and/or osteoporotic vertebral fractures according to WHO criteria, * Patient who were able to ambulate without any assistive devices
Exclusion criteria
* History of neurological disease which may affect balance and proprioception, * Visual and vestibular disease * Previous major lower extremity surgery or previous vertebra surgery * Advanced heart, liver, or renal failure * Stage 4 knee osteoarthritis * Psychiatric disorders * Use of any medication affecting the central nervous system.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| tandem stance and gait test | Data were collected over a single measurement period of 6 months. | static and dynamic balance was measured. |
| berg balance scale | Data were collected over a single measurement period of 6 months. | Berg balance scale was originally developed for the assessment of postural control and is widely used in many areas of rehabilitation. There are 14 items in the scale, like commonly performing in daily activities sitting and standing balance, transfers, turning, and retrieving objects from the floor. The highest total score is 56 points. If the patient scores between 0-20 points, they are considered wheelchair dependent, between 21-40 points they can walk with assistance and between 41-56 points they are considered independent in mobilization activities. |
| Timed up and go test | Data were collected over a single measurement period of 6 months. | There is a significant relationship between TUG times and functional mobility level |
| chair stand test | Data were collected over a single measurement period of 6 months. | The five times CST evaluates the strength, power, and endurance of the lower extremity muscle group, particularly the quadriceps femoris muscle |
| quadriceps femoris muscle thickness | Data were collected over a single measurement period of 6 months. | evaluated by ultrasound |
| thoracic kyphosis | Data were collected over a single measurement period of 6 months. | The lateral thoracic vertebra radiographs were taken while standing position, the Cobb angle was automatically obtained by computer-aided method by marking the parallel lines drawn from the upper edge of the upper thoracic vertebra (T4), and the lower edge of the lower thoracic vertebra (T12) |
Countries
Turkey (Türkiye)
Outcome results
None listed