Neovascular (wet) Age-Related Macular Degeneration
Conditions
Brief summary
The macula has a very high concentration of photoreceptor cells - the cells that detect light. They send signals to the brain, which interprets them as images. The rest of the retina processes our peripheral, or side vision To explore whether cataract surgery evokes development or relapse of choroidal neovascularization (CNV) in wet age-related macular degeneration (AMD) patients followed for a 1-year postoperative period
Detailed description
Age-related macular degeneration (AMD) is a leading cause of vision loss in adults over the age of 50. AMD causes damage to a small part of the retina responsible for central vision called the macula. When damage to the macula occurs, it typically causes loss of central, detailed vision which results in difficulty with tasks such as reading, driving, threading a needle, or recognizing faces. Phacoemulsification is a modern-day cataract surgery that employs ultrasound energy to emulsify the nucleus, vacuum to catch the nuclear material, and irrigation and aspiration for cortex and viscoelastic removal. It is currently impossible to draw definitive conclusions whether phacoemulsification (PhE) is safe for people with age-related macular degeneration (ARMD). It is not clear if PhE causes the progression of ARMD and affects visual acuity (VA). The purpose was to analyze the possible association of PhE with ARMD progression in the early and late (up to 18 months after surgery) period.
Interventions
None listed
Sponsors
Assiut University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Subjects included in this study aged above 50 and presented for routine check up after undergoing phacoemulsification: * Above 50 years old * not diabetic individuals * wet ARMD
Exclusion criteria
* intraoperative complications * Eyes with diseases predisposing them for postoperative macular edema, preexisting macular edema, and eyes that developed cystoid macular edema * active ocular inflammation or infection \_glaucoma * A preoperatively worsened VA regardless phE * ocular trauma * patients with central retinal ischemia * previous vitrectomy * dry amd
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To figure out the possibility of Postoperative conversion or relapse ( Dry to wet , wet to reactivated CNV) | baseline | To explore whether cataract surgery evokes development or relapse of choroidal neovascularization (CNV) in wet age-related macular degeneration (AMD) patients followed for a 1-year postoperative period |
Contacts
Primary ContactDemiana Alkes Zakka Labib Demiana Alkes Zakka Labib
Outcome results
None listed