Impact of Persistent Microvascular Obstruction by Cardiac Magnetic Resonance on Prognosis for ST-segment Elevation Myocardial Infarction

Prognostic Role of Persistent Microvascular Obstruction by Cardiac Magnetic Resonance for ST-segment Elevation Myocardial Infarction

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06759532

Acronym

IMCOME

Enrollment

344

Registered

2025-01-06

Start date

2017-04-01

Completion date

2024-10-20

Last updated

2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ST Elevation (STEMI) Myocardial Infarction

Keywords

Microvascular occlusion;, ST-segment elevation myocardial infarction, Prognosis

Brief summary

The aims of the study were to evaluate the predictive value of persistent microvascular obstruction (MVO) by cardiac magnetic resonance for main adverse cardiac events in ST-segment elevation myocardial infarction patients. MVO in the acute phase of myocardial infarction has been considered to be strong predictor of a poor prognosis. We plan to explore the relationship between persistent MVO and the long-term prognosis of patients with STEMI. We made hypothesis that patients with persistent MVO have a poor prognosis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* ST-segment elevation myocardial infarction undewent primary percutaneous coronary intervention

Exclusion criteria

* contraindications for cardiac magnetic resonance * severe heart failure * previous myocardial infarction.

Design outcomes

Primary

Measure	Time frame	Description
Main aderverse cardiac events	5 years after myocardiac infarction	Composite endpoint of all-cause death, readmission due to heart failure, recurrent myocardial infarction, and unexpected vascularization.

Countries

China

Outcome results