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Comparison of LASER Therapy and Desensitizing Agents in Dentinal Hypersensitivity

Comparison of Mean Pain Score Using LASER Therapy and Desensitizing Agents in Patients With Dentinal Hypersensitivity: A Randomized Controlled Trial

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06759454
Enrollment
172
Registered
2025-01-06
Start date
2025-06-30
Completion date
2026-06-30
Last updated
2025-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentinal Hypersensitivity

Brief summary

This study evaluates the effectiveness of laser therapy versus desensitizing agents in reducing pain among participants with dentinal hypersensitivity conducted in Saidu College of Dentistry. Pain will be measured at baseline, immediately post-treatment, one week, and three months using the Visual Analog Scale (VAS)

Detailed description

This study examines dentinal hypersensitivity treatment modalities, including laser therapy and desensitizing agents. The study is conducted in compliance with regional ethical guidelines

Interventions

DRUGGlutaraldehyde-Based Desensetizing Agent

A glutaraldehyde-based desensitizing agent applied to the cervical area of affected teeth using a micro-brush, left undisturbed for 30 seconds, and air-dried. Both interventions aim to reduce pain associated with dentinal hypersensitivity by either occluding dentinal tubules or reducing nerve excitability

DEVICELow Level Laser Therapy

Low-level laser therapy (LLLT) using a diode laser set to a low power level (e.g., 100 mW, continuous wave mode). Each affected tooth will be treated for three minutes, targeting apical, cervical, and middle points

Sponsors

Kemia Gul
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* Participants aged 18-50 years with a preoperative VAS score of ≥2 for dentinal hypersensitivity. * Participants with sensitivity due to gingival recession, cervical abrasion, or enamel erosion. * Participants with good systemic health. * Minimum of two hypersensitive teeth present in two different quadrants.

Exclusion criteria

* Teeth with caries, defective restorations, or cervical defects \> 2 mm (may affect sensitivity measurements). * Periodontal surgery or deep periodontal pockets (\> 6 mm) within the past three months (potential influence on periodontal health and sensitivity). * Participants using desensitizing toothpaste within the past three months (could interfere with study outcomes). * Presence of gross oral pathology or systemic diseases (e.g., eating disorders, chronic diseases, uncontrolled metabolic conditions) (may alter oral health status). * Pregnant or lactating women (hormonal changes can influence oral health).

Design outcomes

Primary

MeasureTime frameDescription
Change in pain intensity: Visual Analog ScaleImmediately post-treatment, one week, and three monthsAfter intervention there is a possibility of change in pain intensity in Dentinal Hypersensitivity

Countries

Pakistan

Contacts

Primary ContactBrekhna Yousafzai
kemiagul3456@gmail.com+923417262127
Backup ContactKemia Gul
brekhna.apple123@gmail.com+923352803890

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026