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Comparison of Textbook Outcomes Between Laparoscopic and Open Total Gastrectomy for Gastric Cancer

Comparison of Textbook Outcomes Between Laparoscopic and Open Total Gastrectomy for Gastric Cancer

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06758934
Enrollment
94
Registered
2025-01-06
Start date
2024-08-01
Completion date
2024-10-01
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrectomy, Gastric Cancer

Keywords

Total Gastrectomy, Textbook Outcome, Open Gastrectomy, Minimally Invasive Surgery

Brief summary

Gastric cancer patients underwent total gastrectomy with curative intent between in a single center were included in this retrospective study. Patients divided to two groups as open and laparoscopic groups and compared in terms of demographic data, tumor characteristics, operative data and textbook outcome

Detailed description

Gastric cancer patients underwent total gastrectomy with curative intent between July 2018 and January 2024 in a single center were included in this retrospective observational study. Enrolled patients divided to two groups as open total gastrectomy (open group) and laparoscopic total gastrectomy (lap group). Data of patients obtained via the hospital software system. Demographic data, body mass index(BMI), Charlson comorbidity index (CCI) score and baseline characteristics, operative and postoperative results, tumor characteristics and textbook outcome results were investigated. Postoperative complications were pancreatic fistula, pleural effusion, pneumonia, anastomotic leak, intraabdominal abscess, surgical site infection, postoperative ileus. All patients were already curative surgery patients and underwent total gastrectomy and D2 lymphadenectomy. Apart from this, the list of criteria for a patient who had a textbook outcome was as follows: no intraoperative complication, achievement of tumor-negative margins, including ≥15 harvested lymph nodes in resected specimen, no severe postoperative complication(Clavien-Dindo Score≥3, (CD)), no reintervention, no readmission to intensive care unit after once coming to the surgical ward, no prolonged hospital stay (≤21 days), no postoperative mortality (30 days) and no readmission after discharge from the hospital

Interventions

None listed

Sponsors

Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Gastric cancer patients underwent total gastrectomy with curative intent

Exclusion criteria

* Emergency surgery, * Recurrent disease * Metastatic disease, * Conversion to open surgery, * Robotic gastrectomy.

Design outcomes

Primary

MeasureTime frameDescription
Textbook Outcome30 daysThe criteria required for a patient who underwent total gastrectomy to have reached a textbook outcome are as follows: * no intraoperative complication, * achievement of tumor-negative margin, * including ≥15 harvested lymph nodes in resected specimen, * no severe postoperative complication(Clavien-Dindo Score≥3, (CD)), * no reintervention, * no readmission to intensive care unit after once coming to the surgical ward, * no prolonged hospital stay (≤21 days), * no postoperative mortality (30 days) and * no readmission after discharge from the hospital

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026