Sickle Cell Disease
Conditions
Brief summary
pulmonary complications are common in sickle cell disease patients. Respiratory training using inspiratory muscle trainer (IMT) is usually a good choice to improve these complications. Recently, acupuncture like transcutaneous electrical nerve stimulation (AC-tens) may also improve these complications.
Detailed description
sickle cell disease patients whose number will be forty patients will be divided to group I who will trained with IMT (threshold inspiratory muscle training) and treated with AC-tens (the number of patients will be 20) or group II who will trained with IMT (the number of patients will be 20) . The number of sessions per week will be three sessions for IMT or AC-tens for 12 weeks. the IMT will be performed for six sets of respiratory training cycles and the set will contain 10 respiratory cycles. Also the session of AC-tens will be 45 minute on bilateral Ex-B1 acupoint. the parameters of AC-tens will be four hertz and 200 microsecond pulse duration.
Interventions
BEHAVIORALinspiratory muscle training and acupucnture like transcutanoeus electrical nerve stimulation
sickle cell disease patients whose number will be 20 patients will be trained with IMT (threshold inspiratory muscle training) and treated with AC-tens. The number of sessions per week will be three sessions for IMT or AC-tens for 12 weeks. the IMT will be performed for six sets of respiratory training cycles and the set will contain 10 respiratory cycles. Also the session of AC-tens will be 45 minute on bilateral Ex-B1 acupoint. the parameters of AC-tens will be four hertz and 200 microsecond pulse duration.
BEHAVIORALinspiratory muscle training
sickle cell disease patients whose number will be 20 patients who will trained with IMT (threshold inspiratory muscle training). The number of sessions per week will be three sessions for IMT for 12 weeks. the IMT will be performed for six sets of respiratory training cycles and the set will contain 10 respiratory cycles.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* sickle cell disease patients * non obese patients
Exclusion criteria
* patients with any systemic or chest or renal or hepatic or neurological diseases * women with lactation or pregnancy * patients atacks of vasoocclusive crisis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| FEV1/FVC ratio | it will be assessed after12 weeks | will be measured by spirometry |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| forced vital capacity | it will be assessed after12 weeks | will be measured by spirometry |
| six minute walk distance | it will be assessed after12 weeks | it will be a measure of physical capacity |
| physical summary of short form 36 | it will be assessed after12 weeks | it is a questionnaire measure of quality of life |
| forced expiratory volume at the first second of expiration | it will be assessed after12 weeks | will be measured by spirometry |
| right diaphragmatic excrusion | it will be measured after 12 weeks | it will be assessed by ultrasonography |
| left diaphragmatic excrusion | it will be measured after 12 weeks | it will be assessed by ultrasonography |
| mental summary of short form 36 | it will be assessed after12 weeks | it is a questionnaire measure of quality of life |
Countries
Egypt
Contacts
Primary ContactAli Isamil, Lecturer
Backup Contactali ismail, Lecturer
Outcome results
None listed