Oral Mucositis
Conditions
Brief summary
evaluatation the efficacy of Aleovera in prevention and treatment of chemotherapy-induced oral mucositis in children suffering from acute leukemia in terms of appearance and severity
Interventions
OTHERSecond arm: Using aleovera for Prevention and Treatment of Chemotherapy-Induced Oral Mucositis
Second arm : aleovera 3 times daily after brushing teeth
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
3 Years to 13 Years
Healthy volunteers
No
Inclusion criteria
1. Patients suffering from Acute leukemia( Acute Lymphocytic Leukemia ). 2. Patients scheduled for chemotherapy treatment. 3. Patients who range from 3 to 13 years old. 4. Patients with no history of any chemotherapy or radiotherapy. 5 -Both sexes
Exclusion criteria
1-Patients scheduled for radiotherapy treatment . 2-Existence of any signs or symptoms of oral mucositis. 3-Unwilling to participation in the study 4- Patients with any other systemic diseases or other neoplasms.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevention of oral mucositis | 2 months | Assessment the efficacy of aleo vera gel on prevention of chemotherapy-induced oral mucositis through application the gel 3 times daily then patients were assessed daily in terms of appearance and severity of oral mucositis according WHO grading system. The World Health Organization (WHO) mucositis scale is used to grade the severity of oral mucositis. Grade 0: No mucositis Grade 1: Soreness/erythema only. Grade 2: Erythema, and ulcers. Able to tolerate solids. Grade 3: Unable to tolerate solids but able to tolerate liquids. Grade 4: Unable to tolerate solids or liquids. Oral alimentation is not possible. |
Countries
Egypt
Outcome results
None listed