Propofol
Conditions
Brief summary
This study aims to compare efficacy of sedation between Dexmedetomidine-Propofol and Ketamine-Propofol combinations in the upper or lower gastrointestinal system endoscopy. We compare between 2 combinations as regard hemodynamic stability, post operative side effects as occurrence of delirium, nausea, vomiting, headache, hallucination or agitation.
Interventions
efficacy of sedation with Dexmedetomidine-Propofol combination in the upper or lower gastrointestinal system endoscopy.
efficacy of sedation with Ketamine-Propofol combination in the upper or lower gastrointestinal system endoscopy.
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists physical status I to II. * Age between 18 and 60 years. * Both sexes.
Exclusion criteria
* Having severe heart, lung, liver disease, kidney failure, or bleeding disorder. * Patients having fever, hypothermia or infection, electrolyte disorders, such as hypokalemia and hypocalcaemia, acid-base disorder, allergy to drugs to be used.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| intraoperative and postoperative monitoring of sedation during upper or lower gastrointestinal system endoscopy. | every 5 minutes intraoperative and every 15 minutes for 2 hours postoperative. | Sedation level |
Countries
Egypt
Outcome results
None listed