Esophageal Cancer
Conditions
Brief summary
To prospectively collect medical images and clinical data related to esophageal cancer using 4D Free Breathing DCE-MRI technology, to evaluate the image quality in the diagnosis of esophageal cancer, and to predict the efficacy of preoperative neoadjuvant chemoradiotherapy for esophageal cancer.
Interventions
DIAGNOSTIC_TESTThe application value of MRI 4D Free Breathing DCE-MRI in the treatment of esophageal cancer
Chest MRI scan outside of standard treatment options
Sponsors
Yunnan Cancer Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. Be 18 years of age and older; 2. First diagnosis of esophageal squamous cell carcinoma confirmed by histopathological biopsy; 3. The clinical stage is cT1b\ cT2N+; or the clinical stage is cT3\ cT4 any N, (thoracic esophageal cancer, esophagogastric junction cancer); 4. There are no contraindications to MRI examination
Exclusion criteria
1. Have other primary tumors; 2. The image quality does not meet the diagnostic criteria; 3. Those who do not cooperate with the inspection; 4. Patients who have received prior chemoradiotherapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tumor response assessment | Surgery was performed within one month after neoadjuvant therapy, and the pathological pCR of the pathological results obtained from the surgery was used as the gold standard in this study to evaluate tumor treatment response | This study aims to assess tumor treatment response using pathology gold standard pCR . pCR refers to the state in which the pathological tumor completely disappears after systemic therapy, such as chemotherapy, targeted therapy, or endocrine therapy. |
Countries
China
Contacts
Primary Contactruiling Yang
Backup Contactzhenhui Li
Outcome results
None listed