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Clinical Features and Visual Prognosis of Infectious Endophthalmitis

Be Cautious of the Endogenous Endophthalmitis--Clinical Characteristics and Visual Prognosis of 104 Cases of Infectious Endophthalmitis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06755177
Enrollment
100
Registered
2025-01-01
Start date
2024-06-01
Completion date
2024-11-11
Last updated
2025-01-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endophthalmitis

Keywords

Infectious endophthalmitis, Endogenous endophthalmitis, Exogenous endophthalmitis

Brief summary

The aim of this observational study was to retrospectively examine the clinical data of patients with infectious endophthalmitis and to analyse their clinical characteristics. The main question it aims to answer is: to find the differences between endogenous and exogenous endophthalmitis and to provide new ideas for the diagnosis and treatment of infectious endophthalmitis.

Interventions

None listed

Sponsors

Zhongnan Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients diagnosed with infectious endophthalmitis by specialist examination. The clinical diagnosis of endophthalmitis was established on the basis of clinical signs and symptoms, including ocular pain, loss of vision, eyelid oedema, conjunctival congestion, inflammation of the anterior chamber (flare-ups, cells, pupillary fibrin membranes, and pus accumulation in the anterior chamber), vitritis, and vitreous clouding on B-scan ultrasound. The diagnosis of infectious endophthalmitis was clarified by the aqueous vitreous pathogen detection test.

Exclusion criteria

* Patients with incomplete medical records; non-infectious uveitis, retinal tumour disease, ocular ischaemia syndrome and other diseases with similar manifestations to endophthalmitis.

Design outcomes

Primary

MeasureTime frameDescription
visual acuityPre-operative, post-operative follow-up at 1 month, 3 months, 1 year, etc.best-corrected visual acuity (BCVA)

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026