Skip to content

Pulmonary Artery Doppler in Preeclamptic Mothers

Fetal Pulmonary Artery Doppler in Mothers With Preeclampsia for Detecting Neonatal Respiratory Distress

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06755073
Enrollment
86
Registered
2025-01-01
Start date
2024-12-31
Completion date
2025-12-10
Last updated
2026-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Artery Doppler

Keywords

Pulmonary Doppler, Preeclampsia

Brief summary

Evaluation of Pulmonary artery Doppler parameters in fetuses of mothers with severe preeclampsia

Detailed description

Preclampsia (PE) represent a major concern in public health, affecting 2-8% of all pregnancies and considered one of the leading causes of perinatal morbidity and mortality. fetal growth restriction (FGR) ia also a common health problem affecting about 5-10% of all pregnancies and commonly associates with preeclampsia . It is estimated that 20% of cases of PE present with FGR and about 50% of early-onset FGR cases will eventually coexist with PE. Preeclampsia affects about 5% of pregnancies and hypertensive disorders of pregnancy cause over 60,000 maternal fatalities each year around the world .The decision to deliver a woman with severe pre-eclampsia that is far from the term \[mid-trimester\] is difficult for the obstetrician.In most cases of highly premature pre-eclamptic gestation, certain institutions propose continuing pregnancy until one of the following occurs development of fetal lung maturity, development of fetal or maternal discomfort, or accomplishment of gestational age of 34 to 36-week of gestation . Numerous tests have been developed in an attempt to identify if fetal lung maturation has reached a level sufficient to prevent the development of fetal RDS. These tests are based on four core themes: biochemical testing for active surfactant components, biophysical testing for surfactant functionality, physical testing of amniotic fluid opacity, and ultrasound examination of the fetuses and their tissues . Neonatal RDS has been predicted using fetal pulmonary artery Doppler. Kim and colleagues discovered that a high PAT/ET was linked to newborn RDS .The development of RDS in preterm newborns is linked to an increased acceleration time to ejection time \[AT/ET\] ratio in the fetal pulmonary artery .

Interventions

RADIATIONPulmonary artery Doppler ultrasound

Doppler ultrasound of fetal pulmonary artery

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

* preeclampsia patients Pregnant 28 -37 weeks

Exclusion criteria

* fetal death Congenital fetal anomalies Fetal Cardiac arrhythmia

Design outcomes

Primary

MeasureTime frameDescription
Pulmonary Doppler resistance index1 monthPulmonary Doppler index in fetus of preeclamptic mother

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 8, 2026